小儿紫癜性肾炎的临床病理及远期预后分析

周玲, 陈钟, 贾劬

中国当代儿科杂志 ›› 2001, Vol. 3 ›› Issue (2) : 139-140.

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中国当代儿科杂志 ›› 2001, Vol. 3 ›› Issue (2) : 139-140.
论著

小儿紫癜性肾炎的临床病理及远期预后分析

  • 周玲,陈钟,贾劬
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Clinical Pathology and Long Term Prognosis of HenochSchonlein Nephritis in Children

  • ZHOU Ling, CHEN Zhong, JIA Qu
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摘要

目的:分析小儿紫癜性肾炎的临床、病理与远期预后的关系。方法:比较32例紫癜性肾炎的临床病理变化,随访其中19例,随访期限8~14年,了解临床及病理对远期预后的影响。结果:小儿紫癜性肾炎的临床分型中以急性肾炎综合征型多见,占50%,肾病综合征型次之占40%;病理变化以Ⅱ~Ⅲ级多见。急性肾炎综合征型与肾病综合征型随访比较,痊愈率分别为55.6%(5/9例)和28.6%(2/7例);病理分级Ⅰ~Ⅲ级的痊愈率为43.8%(7/16例),恶化率12.5%(2/16例),Ⅳ~Ⅴ级中66.7%(2/3例)恶化或死亡。结论:急性肾炎综合征型远期预后较肾病综合征型好,远期预后与临床分型及病理分级密切相关。

Abstract

OBJECTIVE: To analyze the relationship between the clinical and pathological effects and longterm prognosis in children with Henoch Schonlein nephritis. METHODS: Changes of clinical pathology were studied in 32 children with Henoch Schonlein nephritis and 19 cases of them were followed over an 8 to 14 year period. RESULTS: Acute nephritis ranked first (50%) and the nephritic syndrome ranked second (40%) in the clinical classification of Henoch Schonlein nephritis; the majority had pathological changes of Grade Ⅱ~Ⅲ. The rate of recovery of acute nephritis and the nephritic syndrome was 55.6% and 28.6%, respectively. The rate of recovery and deterioration of Grade Ⅰ~Ⅲ pathological changes was 43.8% and 12.5%, respectively. Of the patients with Grade Ⅳ~Ⅴ pathological changes, 66.7% deteriorated or died. CONCLUSIONS: The prognosis of acute nephritis was better than that of the nephritic syndrome, and longterm prognosis is closely associated with the clinical classification and pathology

关键词

紫癜性肾炎 / 临床 / 病理 / 远期预后 / 儿童

Key words

Henoch Schonlein nephritis / Clinical / Pathological / Long term prognosis / Child

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导出引用
周玲, 陈钟, 贾劬. 小儿紫癜性肾炎的临床病理及远期预后分析[J]. 中国当代儿科杂志. 2001, 3(2): 139-140
ZHOU Ling, CHEN Zhong, JIA Qu. Clinical Pathology and Long Term Prognosis of HenochSchonlein Nephritis in Children[J]. Chinese Journal of Contemporary Pediatrics. 2001, 3(2): 139-140
中图分类号: R692.3 +4   

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