Phadiatop和sIgE检测在儿童哮喘诊断中的应用

雷其洪, 葛传生, 季纯珍, 姚劲, 赵德育, 赵维美

中国当代儿科杂志 ›› 2001, Vol. 3 ›› Issue (5) : 501-502.

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中国当代儿科杂志 ›› 2001, Vol. 3 ›› Issue (5) : 501-502.
论著

Phadiatop和sIgE检测在儿童哮喘诊断中的应用

  • 雷其洪,葛传生,季纯珍,姚劲,赵德育,赵维美
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Application of Phadiatop Test and Specific IgE Test in theDiagnosis of Children with Asthma

  • LEI Qi-Hong, GE Chuan-Sheng, JI Chun-Zhen, YAO Jin, ZHAO De-Yu, ZHAO Wei-Mei
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摘要

目的:探讨CAP过敏原检测系统中吸入性过敏原过筛试验(Phadiatop)检测和特异性IgE(sIgE)检测在小儿哮喘病因诊断中的价值。方法:应用荧光酶联免疫法,对153例小儿哮喘、40例支气管肺炎进行Phadiatop,sIgE和血清总IgE检测。结果:哮喘患儿Phadiatop和尘螨sIgE阳性率分别为 66.01%和59.48%,而支气管肺炎患儿两者阳性率分别为 12.5%和7.5%,两组间差异有显著性(P<0.05)。Phadiatop,sIgE灵敏度分别为0.66和0.59,特异度分别为0.88和0.93,两种检测的一致性高。结论:Phadiatop检测是哮喘病因诊断简便、可靠的体外过筛试验,Phadiatop阳性患儿应进一步作sIgE检测。

Abstract

OBJECTIVE: To explore the value of Phadiatop test and specific IgE test in the diagnosis of children with asthma. METHODS: Using Flo ELISA, Phadiatop, specific IgE and total IgE of serum were determined in 153 cases with asthma and 40 cases with bronchopneumonia. RESULTS: The positive rates of Phadiatop and specific IgE in the asthma group (66.01% and 59.48%, respectively) were significantly higher than those in the bronchopneumonia group (12.5% and 7.5%, respectively)(P<0.05). Phadiatop test had a sensitivity of 0.66 and a specificity of 0.88, and sIgE test to dust mite had a sensitivity of 0.59 and a specificity of 0.93 respectively. There was a concordant result of 94% between the two tests. CONCLUSIONS: Phadiatop test is a useful screening test for the diagnosis of asthma. sIgE test is further needed for the Phadiatop test positive cases.

关键词

支气管哮喘 / CAP过敏原检测系统 / Phadiatop / 特异性IgE / 儿童

Key words

Asthma / CAP system / Phadiatop / Specific IgE / Child

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导出引用
雷其洪, 葛传生, 季纯珍, 姚劲, 赵德育, 赵维美. Phadiatop和sIgE检测在儿童哮喘诊断中的应用[J]. 中国当代儿科杂志. 2001, 3(5): 501-502
LEI Qi-Hong, GE Chuan-Sheng, JI Chun-Zhen, YAO Jin, ZHAO De-Yu, ZHAO Wei-Mei. Application of Phadiatop Test and Specific IgE Test in theDiagnosis of Children with Asthma[J]. Chinese Journal of Contemporary Pediatrics. 2001, 3(5): 501-502
中图分类号: R562.2+5   

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