报道1例颅内全静脉窦血栓病例,探讨颅内静脉窦血栓的临床特征和诊治方法。8岁男童,因阵发性头痛,呕吐50d,复视2d就诊,经头颅MRI及磁共振静脉成像(MRV)确诊为颅内全静脉窦血栓。经降颅压、静脉滴注尿激酶和激素治疗,临床症状消失,继续口服华法令治疗。头痛、视乳头水肿是颅内静脉窦血栓的主要表现,头颅MRI和MRV是诊断的主要依据。

Cerebral venous sinus thrombosis (CVST) rarely occurs in children but has a mortality rate as high as 20%-78%. Because the clinical manifestation of this disease has no specificity it is easy to be misdiagnosed. This paper reported a case of CVST and reviewed the relevant literatures regarding to the pathogenesis, clinical and pathological features, diagnosis and treatment. The patient (male, 8 months old) was referred to the Beijing Children's Hospital with paroxysm headache and after vomiting for 50 days and having double visions for 2 days. He was definitely diagnosed with CVST by magnetic resonance imaging (MRI) and magnetic resonance venography (MRV). His neurological symptoms were improved after receiving intravenous urokinase and hormonal therapy for three weeks followed by oral anticoagulation. It is concluded that headache and papilledema are the most frequent symptoms in CVST and that MRI and MRV may be primal methods for the diagnosis of CVST.