目的：探讨再发川崎病的临床特点及与冠状动脉病变的关系。方法：收集该院1998年1月至2007年5月收治的再发川崎病20 例,分析临床特点及相关实验室数据。结果：收治初发的1 489例川崎病中,再发20 例,再发率为1.34%,再发间期1.2年。再发病例临床病情较初发轻,症状不典型或复杂，热程、血小板、C反应蛋白和红细胞沉降率较初发时明显降低，但冠状动脉损伤发生率显著高于初发组（40% vs 25%, P<0.05）。结论：再发川崎病临床症状不典型，冠状动脉损伤发生率增高。川崎病再发为川崎病并发冠状动脉损伤的高危因素之一,应加强早期诊断和治疗。［中国当代儿科杂志，2008，10（5）：617-619］

OBJECTIVE: To investigate the clinical features of recurrent Kawasaki disease (KD) and the relationship of recurrent KD with coronary artery lesions. METHODS: The medical data of 20 children with recurrent KD who were admitted to the Children's Hospital from January 1998 to May 2007 were retrospectively studied. Their clinical features were compared with those of children with initial KD. RESULTS: The incidence of recurrent KD was 1.34% (20/1 489). KD relapsed 2 months to 4.6 years (average: 1.2 years) after the first episode in the 20 children. Compared with the initial KD group, the clinical symptoms in the recurrent KD group were incomplete, complicated and less severe. The period of fever, platelet count, C-reactive protein and ESR were remarkably reduced in the recurrent KD group, but the incidence of coronary artery lesions increased significantly compared with the initial KD group (40% vs 25%; P<0.05). CONCLUSIONS: The clinical symptoms of recurrent KD were incomplete in children. Recurrent KD was associated with an increased incidence of coronary artery lesions.［Chin J Contemp Pediatr, 2008, 10 (5):617-619］