早产儿院内感染危险因素及病原学分析

王玉红, 夏世文

中国当代儿科杂志 ›› 2009, Vol. 11 ›› Issue (12) : 980-982.

PDF(997 KB)
PDF(997 KB)
中国当代儿科杂志 ›› 2009, Vol. 11 ›› Issue (12) : 980-982.
论著·临床研究

早产儿院内感染危险因素及病原学分析

  • 王玉红,夏世文
作者信息 +

Risk factors and pathogens of nosocomial infection in preterm infants

  • WANG Yu-Hong, XIA Shi-Wen
Author information +
文章历史 +

摘要

目的:分析早产儿院内感染发生的高危因素及病原学特点。方法:对197例早产儿院内感染情况进行回顾性分析。结果:住院早产儿院内感染发生率为22.2%(197/887)。胎龄小、低出生体重、机械通气治疗、延迟喂养是早产儿发生院内感染的重要高危因素。肺炎克雷伯菌在院内感染中占据首位(22.3%),其次为葡萄球菌(18.4%)。结论:对胎龄小、低出生体重的早产儿应强调以洗手为中心的消毒隔离制度,尽量减少侵入性操作,尽早开始胃肠道喂养,以减少早产儿院内感染的发生。肺炎克雷伯菌是早产儿院内感染的主要病原菌。[中国当代儿科杂志,2009,11(12):980-982]

Abstract

OBJECTIVE: To investigate the risk factors and the pathogens of nosocomial infection in preterm infants. METHODS: The medical data of 197 preterm infants with nosocomial infection were retrospectively studied. RESULTS: The incidence of nosocomial infection was 22.2% (197/887). Small gestational age (OR=4.125, P<0.05), low birth weight (OR=5.450, P<0.05), mechanical ventilation therapy (OR=4.435, P<0.05) and delayed enteral feedings (OR=3.765, P<0.05) were found to be important risk factors for nosocomial infection. Klebsiella was the main pathogen (22.3%), followed by Staphylococcus (18.4%). CONCLUSIONS: Hygienic handwashing, decreasing invassive procedures and an early start of enteral feeding are crucial for preventing nosocomal infection in preterm infants. Klebsiella is the main pathogen of nosocomal infections[Chin J Contemp Pediatr, 2009, 11 (12):980-982]

关键词

院内感染 / 危险因素 / 早产儿

Key words

Nosocomial infection / Risk factor / Preterm infant

引用本文

导出引用
王玉红, 夏世文. 早产儿院内感染危险因素及病原学分析[J]. 中国当代儿科杂志. 2009, 11(12): 980-982
WANG Yu-Hong, XIA Shi-Wen. Risk factors and pathogens of nosocomial infection in preterm infants[J]. Chinese Journal of Contemporary Pediatrics. 2009, 11(12): 980-982
中图分类号: R722.13   

参考文献

[1]Carey AJ, Saiman L, Polin RA. Hospital-acquired infections in the NICU: epidemiology for the new millennium[J]. Clin Perinatol, 2008, 35(1):223-49.
[2]Newby J. Nosocomial infection in neonates: inevitable or preventable?[J]. J Perinat Neonatal Nurs, 2008, 22(3):221-227.
[3]杨琳琳, 陈运斌. 丙种球蛋白治疗早产儿呼吸机相关性肺炎疗效观察[J].中国妇幼保健, 2003, 18(9):50-51.
[4]Horii KA, Nopper AJ. Emerging cutaneous infections in the premature neonate[J]. Adv Dermatol, 2007, 23:177-195.
[5]Benjamin DK Jr, Stoll BJ, Fanaroff AA, McDonald SA, Oh W, Higgins RD, et al. Neonatal candidiasis among extremely low birth weight infants: risk factors, motality rates, and neurodevelopmental outcome at 18 to 22 months[J]. Pediatrics, 2006, 117(1):84-92.
[6]丁艳,沈月华,施婴婴.新生儿重症监护室肺炎克雷伯菌败血症危险因素及临床特征[J].中国新生儿科杂志, 2008, 23(6):334-335.
[7]Soltau TD, Schelonka RL. Immune modification to prevent nosocomial sepsis in hospitalized newborns[J]. NeoRreviews, 2008, 9(5):199-205.
[8]Lemus-Varela Mde L, Alberto VS, Arriaga-Dávila Jde J. Clinical and laboratory parameters in neonatal nosocomial sepsis[J].  Gac Med Mex, 2008, 144(5):409-411.


PDF(997 KB)

Accesses

Citation

Detail

段落导航
相关文章

/