高效抗逆转录病毒治疗小儿艾滋病临床分析

郝锦丽, 王宝金, Jean BAPTISTE

中国当代儿科杂志 ›› 2010, Vol. 12 ›› Issue (11) : 874-876.

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中国当代儿科杂志 ›› 2010, Vol. 12 ›› Issue (11) : 874-876.
论著·临床研究

高效抗逆转录病毒治疗小儿艾滋病临床分析

  • 郝锦丽,王宝金,Jean BAPTISTE
作者信息 +

Efficacy of highly active antiretroviral therapy for childhood acquired immunodeficiency syndrome

  • HAO Jin-Li, WANG Bao-Jin, Jean BAPTISTE
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文章历史 +

摘要

目的:探讨高效抗逆转录病毒治疗(HAART)对儿童艾滋病(AIDS)的治疗效果。方法:回顾性分析非洲卢旺达某地区38例2~15岁HAART治疗的AIDS患儿的临床资料。结果:(1)38例AIDS患儿中13例贫血患儿情况均得到改善,其中12例轻中度贫血患儿血红蛋白均恢复到正常水平;(2)6例重度免疫抑制患儿中5例CD4 T淋巴细胞数有明显提高,增长24%~1 181%;(3)HAART治疗期间,患儿体重增长年平均为2.3 kg;治疗前发育迟缓的8例患儿有5例恢复到当地同年龄组正常水平。结论:HAART可改善AIDS患儿健康情况,是儿童AIDS患儿的有效选择。[中国当代儿科杂志,2010,12(11):874-876]

Abstract

OBJECTIVE: To investigate the efficacy of highly active antiretroviral therapy (HAART) for acquired immunodeficiency syndrome (AIDS) in children. METHODS: The clinical data of 38 children (2-15 years old) with AIDS from a region of Rwanda and who had received HAART were retrospectively reviewed. RESULTS: All of 13 children with anemia showed improved anemia symptoms after HAART. The hemoglobin contents returned to normal levels in 12 children with mild or moderate anemia. CD4 T lymphocytes increased by 24%-1 181% in 5 out of 6 cases with severe immunodeficiency after HAART. During the HAART, the weight gain averaged 2.3 kg yearly. The growth and development in 5 out of 8 children with delayed growth restored the levels of normal children of the same age after HAART. CONCLUSIONS: HAART can improve the health status in children with AIDS and is effective for childhood AIDS.[Chin J Contemp Pediatr, 2010, 12 (11):874-876]

关键词

艾滋病 / 高效抗逆转录病毒治疗 / 儿童

Key words

Acquired immunodeficiency syndrome / High active antiretroviral therapy / Child

引用本文

导出引用
郝锦丽, 王宝金, Jean BAPTISTE. 高效抗逆转录病毒治疗小儿艾滋病临床分析[J]. 中国当代儿科杂志. 2010, 12(11): 874-876
HAO Jin-Li, WANG Bao-Jin, Jean BAPTISTE. Efficacy of highly active antiretroviral therapy for childhood acquired immunodeficiency syndrome[J]. Chinese Journal of Contemporary Pediatrics. 2010, 12(11): 874-876
中图分类号: R512.91   

参考文献

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