儿童慢波睡眠期持续性棘慢复合波综合征的特征

王莲, 邓艳春, 刘永红, 黄远桂

中国当代儿科杂志 ›› 2010, Vol. 12 ›› Issue (2) : 93-95.

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中国当代儿科杂志 ›› 2010, Vol. 12 ›› Issue (2) : 93-95.
论著·临床研究

儿童慢波睡眠期持续性棘慢复合波综合征的特征

  • 王莲,邓艳春,刘永红,黄远桂
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Characteristics of continuous spike-and-wave during slow wave sleep syndrome in children

  • WANG Lian, DENG Yan-Chun, LIU Yong-Hong, HUANG Yuan-Gui
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摘要

目的:慢波睡眠期持续性棘慢复合波(CSWS)综合征为睡眠期癫癎性电持续状态(ESES)的表现之一。该研究旨在评价CSWS综合征的特征,提高对该病的认识。方法:对2007~2009年期间记录的778个夜间长程或24小时视频脑电图监测结果进行研究,对符合CSWS标准的患儿的脑电图、临床表现和神经影像学特征进行分析总结。结果:9例患儿的视频脑电图结果符合CSWS诊断标准,年龄6~13岁,脑电图表现为棘慢复合波在整个非快速眼动(NREM)睡眠期几乎持续存在,其放电时间占整个NREM期的85%~100%;临床上患者表现不同类型的癫癎发作,在神经精神方面存在不同程度的损害,存在言语和/或行为障碍;其中6例患儿显示有神经影像学异常,包括脑发育不全或萎缩、灰质异位、脑白质软化等。结论:对CSWS综合征的特征进行评价有助于对该病的认识及诊治。[中国当代儿科杂志,2010,12(2):93-95]

Abstract

OBJECTIVE: Continuous spike-and-wave during slow wave sleep (CSWS) syndrome is one of the presentations of electrical status epilepticus during sleep (ESES). The purpose of this study was to investigate the characteristics of CSWS syndrome in children. METHODS: Between 2007 and 2009, a total of 778 nocturnal long-term or 24-hr video-EEG records were included. The EEG, clinical and neuroimaging characteristics were studied in children who met standard criteria for CSWS. RESULTS: Nine children met standard criteria for CSWS in video-EEGs. Their ages ranged 6 to 13 years. Their EEGs were characterized by continuous spike-and-wave (SW) discharges during non-rapid eye movement (NREM) sleep, accounting for 85%-100% of the period of NREM sleep. Clinically, these children had various types of epileptic seizures and exhibited different degrees of neuropsychiatric impairments, language dysfunction, and/or behavioral disturbances. Neuroimaging abnormalities were found in 6 cases, including atelencephalia or atrophy, gray matter heterotopia and leucomalacia. CONCLUSIONS: This study indicates the characteristics of CSWS syndrome in clinical manifestations, EEG and neuroimaging examinations. This will be helpful in understanding CSWS syndrome.[Chin J Contemp Pediatr, 2010, 12 (2):93-95]

关键词

睡眠期癫癎性电持续状态 / 慢波睡眠期持续性棘慢复合波 / 儿童

Key words

Electrical status epilepticus during sleep / Continuous spike-and-wave during slow wave sleep / Child

引用本文

导出引用
王莲, 邓艳春, 刘永红, 黄远桂. 儿童慢波睡眠期持续性棘慢复合波综合征的特征[J]. 中国当代儿科杂志. 2010, 12(2): 93-95
WANG Lian, DENG Yan-Chun, LIU Yong-Hong, HUANG Yuan-Gui. Characteristics of continuous spike-and-wave during slow wave sleep syndrome in children[J]. Chinese Journal of Contemporary Pediatrics. 2010, 12(2): 93-95
中图分类号: R748   

参考文献

[1]Lucey BP, Duntley SP. Electrical status epilepticus during sleep in an adult[J]. Sleep Med, 2008, 9(3):332-334.
[2]Tassinari CA, Michelucci R, Forti A, Salvi F, Plasmati R, Rubboli G, et al. The electrical status epilepticus syndrome[J]. Epilepsy Res Suppl, 1992, 6:111-115.
[3]Van Hirtum-Das M, Licht EA, Koh S, Wu JY, Shields WD, Sankar R. Children with ESES: variability in the syndrome [J]. Epilepsy Res, 2006, 70(Suppl 1):S248-258.
[4]De Negri M. Electrical status epilepticus during sleep (ESES). Different clinical syndromes: towards a unifying view? [J]. Brain Dev, 1997, 19(7):447-451.
[5]Nickels K, Wirrell E. Electrical status epilepticus in sleep[J]. Semin Pediatr Neurol, 2008, 15(2):50-60.


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