Abstract： Neonatal hypoxic2ischemic encephalopathy (HIE) is a severe complication of perinatal asphyxia. There
are differences in the diagnostic criteria for HIE between China and overseas. The criteria of China do not include blood
gas results of umbilical artery and incidence of multiple organs disorder (MOD) and can easily lead to misdiagnosis , while
the oversea criteria are more scientific , perfect but over2strict which may result in missed diagnosis. At present , there are
no highly specific and sensitive indexes for its diagnosis. So it is suggested that a diagnosis of HIE should be made
according to history ,Apgar score , blood gas results , incidence of MOD ,brain images and clinic manifestations , etc.
