OBJECTIVE: To study the characteristics of bone mineral content (BMC) accretion and the correlation with sex maturity and physical development in adolescents. METHODS: In 161 healthy children aged 9~20 years, the BMC and total alkaline phosphatase (TALP) level were measured using the single photon absorptiometer (SPA) and biochemical methods respectively; the serum levels of bone gla protein (BGP), estrogen and testosterone were determined using RIA; the height and weight were measured routinely and the sex maturity rating was assessed using the Tanner's criteria. RESULTS: The periods of peak height and weight velocity in boys and girls were 11.5 ~13.7 and 9.7 ~11.3 years respectively. The peak BMC accrual occurred in 13.7~16.2 and 11.3 ~13.7 years in boys and girls respectively. BMC accretion in females was earlier compared with males and revealed a significant decline after 16 years of age. The accretion of BMC was highly correlated with the sex maturity rating and there were significant differences in BMC between different pubertal stages (P<0.01). The positive correlations between serum BGP and TALP levels and age were noted (r= 0.59 and r= 0.63 , respectively, both P< 0.01 ). The periods of peak serum BGP and ALP levels and peak height velocity (PHV) were coincident. CONCLUSIONS: There is a close correlation between BMC accretion and sex maturity. There is an asynchrony between BMC accrual and physical development in puberty.

"/> 青春期骨矿物含量与血清骨钙素及碱性磷酸酶的关系
中国当代儿科杂志
  中文版
  English Version
  ISSN 2096-9228(online)
ISSN 1008-8830(print)
CN 43-1301/R
 
中国当代儿科杂志  2002, Vol. 4 Issue (1): 11-14    DOI:
论著 最新目录| 下期目录| 过刊浏览| 高级检索 |
青春期骨矿物含量与血清骨钙素及碱性磷酸酶的关系
李继斌,黎海芪,王松艳,胡怡
重庆医科大学营养学教研室,重庆400016
Relationship between Bone Mineral Content and Serum Bone-Gla-Protein and Alkaline Phosphatase Levels in Puberty
LI Ji-Bin, LI Hai-Qi, WANG Song-Yan, et al.
Department of Nutriology, Chongqing University of Medical Sciences, Chongqing 400016, China
版权所有 ©《中国当代儿科杂志》编辑部
地址:湖南省长沙市湘雅路87号 电话:0731-84327402  传真:0731-84327922 E-mail: cjcp1999@csu.edu.cn 
本系统由北京玛格泰克科技发展有限公司设计开发 技术支持:support@magtech.com.cn
湘ICP备17021739号-4