Abstract：OBJECTIVE: To study the changes in Nacety-β-D-amino glucosidase (NAG) and urinary retinal binding protein (RBP) observed after renal function impairment in asphyxiated newborns. METHODS: Colorimetry of p nitrophoenol and ELISA were adopted to detect the activity of NAG and the content of RBP in asphyxiated full term and premature infants on days 1, 3 and 7, and in matched nonasphyxiated control infants. RESULTS: The levels of NAG and RBP were higher in both asphyxiated full term and premature infants than in the control group (P0.05). CONCLUSIONS: NAG and RBP appear to be indexes of early diagnosis in renal dysfunction in asphyxiated infants, and RBP is a more sensitive one.
LU Qin,LU Chang-Dong,REN Jian-Hua et al. Changes of Nacety-β-D-AminoGlucosidase and Urinary Retinal Binding Protein in Newborns with Asphyxia Complicated by Renal Function Impairment[J]. CJCP, 2001, 3(3): 218-220.
