Abstract:Objective To study the alterations of micro-albuminuria (including IgG, Alb and β 2M) in childten with mycoplasma pneumoniae (MP) pneumonia. Methods Radioimmunoassay was used to detect the alterations of micro-albuminuria of mycoplasma pneumonia at different periods ( 46 cases at the acute period and 36 cases at the recovery period ). Thirty normal children were observed as the control group. Results Microalbuminuria levels of the acute period were significantly higher than those of the normal control group (P<0.01). The increase of micro-albuminuria levels was significantly correlated with exacerbation of the illness. During the recovery period, the level of IgG in the urine was reduced first (P>0.05); although the levels of Alb and β 2M in the urine were reduced obviously, they were still higher than that of the normal control group (P<0.05, P<0.01). Conclusions There are different degrees of kidney impairment in MP pneumonia children. Attention should be paid to protect kidnay function during the treatment of MP pneumonia.