Abstract：Objective To identify the effect of simple obestity on cardiovascular system in children. Methods Left ventricular(LV)structure and function were examined with conventional echocardiography and Doppler tissue imaging techniques in 63 children aged from 7 to 14 years with moderate or severe simple obesity (obesity group) and 63 normal weight children of similar age, height and sex proportion (control group).The relationship between LV structure and function and the degree of obesity was analyzed. Results ①LV diastolic dimension(LVDD),interventricular septal thickness(IVS),LV posterior wall(LVPW) thickness and LV mass (LVM) in obesity group increased significantly as compared with control group ( P <0.01), while LVM index(LVMI)had no obvious change ( P >0.05). Stroke index(SI)and cardiac index(CI)decreased significantly ( P <0.01).There were marked changes in transmitral peak flow velocity during the late atrial filling (A peak),E/A, the motion velocity gaps between LV posterior wall's endocardium and epicardium during early diastolic period (DmeVG), mitral annular early and late diastolic velocity (DeV and DaV), and DeV/aV( P <0.01). ② In obesity group, LVM and some indices about diastolic function showed a correlation with body weight and subcutaneous fat thickness ( P <0.05), but no relationship with the ratio of waist to buttock ( P >0.05). ③ LVM was linearly related to DaV and DeV/aV( P <0.05). Conclusions Obesity in children causes left heart hypertrophy and reduces heart function which is correlated with body weight and subcutaneous fat thickness. LVMI has little change in obese children, which differs from adult obesity. Because childhood obesity is characterized of peripheral fat distribution, the ratio of waist to buttcock is not associated with LV hypertrophy or decreased heart function.
MAO Xia,MA Pei-Ran,JIN Chao et al. Examination of left ventricular struction in children with simple obesity by using conventional echocardiography and Doppler tissue image[J]. CJCP, 1999, 1(2): 71-74.
