晚期早产儿&mdash;大自然未完成的杰作

Raja Nandyal; Kris Sekar

doi:10.7499/j.issn.1008-8830.2013.12.001

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中国当代儿科杂志 ›› 2013, Vol. 15 ›› Issue (12) : 1037-1044. DOI: 10.7499/j.issn.1008-8830.2013.12.001

专家讲座

晚期早产儿—大自然未完成的杰作

Raja Nandyal, Kris Sekar

作者信息 +

Late preterm infant——Nature’s unfinished master piece

Raja Nandyal, Kris Sekar

Author information +

文章历史 +

摘要

晚期早产儿（late preterm infants）是指胎龄为34~36⁺⁶周的早产儿。由于生理和代谢功能不成熟，与足月儿相比，晚期早产儿发病率和病死率较高。晚期早产儿是“极好的冒充者和假装者”，因为他们冒充并假装成足月儿。因其体型大小与足月儿相似，他们常常被当作足月儿，从而造成潜在的不良后果。本综述阐述了晚期早产的发生率和高危因素、早期疾病、晚期并发症，以及医疗护理。我们使用关键词“晚期早产儿”和“近足月儿”对2005年1月至2012年3月期间PubMed、OVID、Embase等计算机数据库的文献进行了检索。通过详细检索，我们获得了用于晚期早产儿监护的一些循证指南。

Abstract

Late preterm infants (LPI) are preterm infants born at a gestational age between 34 and 0/7 weeks to 36 6/7 weeks. Because of their physiologic and metabolic immaturities, they are at increased risk for a spectrum of morbidities and mortality when compared to the term infants. LPI are "great pretenders and masqueraders", as they pretend to be and masquerading as term infants. Because of their size, frequently they are treated as term infants with potential for bad consequences. In this review, the incidence and high risk factors for late preterm deliveries, early morbidities, late complications and management are described. Computerized data bases such as PubMed, OVID and Embase were searched between January 2005 and March 2012, by using the search terms, Late Preterm Infants and Near Term Infants. From this detailed search available, evidence based guidelines were incorporated in the care of these LPI.

导出引用

Raja Nandyal, Kris Sekar. 晚期早产儿—大自然未完成的杰作[J]. 中国当代儿科杂志. 2013, 15(12): 1037-1044 https://doi.org/10.7499/j.issn.1008-8830.2013.12.001

Raja Nandyal, Kris Sekar. Late preterm infant——Nature’s unfinished master piece[J]. Chinese Journal of Contemporary Pediatrics. 2013, 15(12): 1037-1044 https://doi.org/10.7499/j.issn.1008-8830.2013.12.001

参考文献

[1] Raju TN, Higgins RD, Stark AR, Leveno KJ. Optimizing care and outcome for late-preterm (near-term) infants: A Summary of the Workshop sponsored by the National Institute of Child Health and Human Development[J]. Pediatrics, 2006, 118: 1207-1214.
[2] Engle WA. A recommendation for the definition of "late preterm (near term) and the birth weight system[J]. Semin Perinatol, 2006, 30 (1): 2-73.
[3] Engle WA. Morbidity and mortality in late preterm and early term newborns: a continuum[J]. Clin Perinatol, 2011, 38(3): 493-516.
[4] Kashu M, Narayanan M, Bhargava S, Osiovich H. Perinatal outcomes associated with preterm birth at 33 to 36 weeks' gestation: a population-based cohort study[J]. Pediatrics, 2009, 123(1): 109-113.
[5] Selo-Ojme DO, Tewari R. Late preterm (32-36 weeks) birth in a North London hospital[J]. J Obstet Gynaecol, 2006, 26: 624-626.
[6] Laughon SK, Reddy UM, Sun L, Zhang J. Precursors for late preterm birth in singleton gestations[J]. Obstet Gynecol, 2010, 116(5): 1047-1055.
[7] Loftin RW, Habli M, Snyder CC, Cormier CM, Lewis DF, Defranco EA. Late preterm birth[J]. Rev Obstet Gynecol, 2010, 3(1): 1-9.
[8] Holland MG, Refuerzo JS, Ramin SM, Saade GR, Blackwell SC. Late preterm birth: how often is it avoidable?[J]. Am J Obstet Gynecol, 2009, 201 (404): e1-4.
[9] Reddy UM, Ko CW, Raju TN, Willinger M. Delivery indications at late preterm gestations and infant mortality rates in the United States[J]. Pediatrics, 2009, 124(1): 234-240.
[10] Tomashek KM, Shapiro-Mendoza CK, Davidoff MJ, Petrini JR. Differences in mortality between late-preterm and term singleton infants in the United States, 1995-2002[J]. J Pediatr, 2007, 151(5): 450-456.
[11] March of Dimes Perinatal Data Center 2007[EB//OL].[April 2, 2013]. www.marchofdimes.com/peristats.
[12] Melamed N, Klinger G, Tenenbaum-Gavish K, Herscovici T, Linder N, Hod M, et al. Short-term neonatal outcome in low risk, spontaneous, singleton, late preterm deliveries[J]. Obstet Gynecol, 2009, 114(2 Pt 1): 253-260.
[13] Guoyon JB, Vintejoux A, Sagot P, Burguet A, Quantin C, Ferdynus C, et al. Burgundy Perinatal Network. Neonatal outcome associated with singleton birth at 34-41 weeks of gestation[J]. Int J Epidemiol, 2010, 39(3): 769-776.
[14] Shapiro-Mendoza CK, Tomashek KM, Kotelchuck M, Barfield W, Nannini A, Weiss J, et al. Effect of late preterm birth and maternal conditions on newborn morbidity risk[J]. Pediatrics, 2008, 121(2): e223-232.
[15] Wang ML, Dorer DJ, Fleming M, Catlin EA. Clinical outcomes of near-term infants[J]. Pediatrics, 2004, 114(2): 372-376.
[16] Shapiro-Mendoza CK, Tomashek KM, Kotelchuck M, Barfield W, Weiss J, Evans S. Risk factors for neonatal morbidity and mortality among "Healthy", late preterm newborns[J]. Semin Pernatol, 2006, 30 (2): 54-56.
[17] Petrini JR, Dias T, McCormick MC, Massolo ML, Green NS, Escobar GJ. Increased risk of adverse neurological development of late preterm infants[J]. J Pediatr, 2009, 154(2): 169-176.
[18] Lindstrom K, Lindbald F, Hjern A. Psychiatric morbidity in adolescent and young adults born preterm: a Swedish national cohort study[J]. Pediatrics, 2009, 123(1): e47-53.
[19] Morse SB, Zheng H, Tang T, Roth J. Early school-age outcomes of late preterm infants[J]. Pediatrics, 2009, 123(4): e622-629.
[20] Chyi LJ, Lee HC, Hintz SR, Gould JB, Sutcliffe TL. School outcomes of late preterm infants: Special needs and challenges for infants at 32 to 36 weeks gestation[J]. J Pediatr, 2008, 143(1): 25-31.
[21] Oklahoma Infant Alliance. Caring for the late preterm infant: A Clinical Practice Guideline[EB/OL].[Sept 2010]. www.oklahomainfantalliance.org//LPI.
[22] Ma X, Huang C, Lou S, Lv Q, Su W, Tan J, et al. Provincial Collaborative Study Group for Late-preterm Infants. The clinical outcomes of late preterm infants: a multi-center survey of Zhejiang, China[J]. J Perinat Mede, 2009, 37(6): 695-699.
[23] Xu P, Zhang XF, Li Y, Liu XM, Qian SY. Health status and affecting factors of late-preterm infants[J]. Zhonghua Er Ke Za Zhi, 2009, 47(12): 931-934.