Abstract：Objective To study the diagnostic values of cerebrospinal concentrations of neopterin (NPT) and S100b for central nervous system infections in children. Methods Enzyme-linked immunosorbent assay was used to determinate the cerebrospinal concentrations of NPT and S100b in children with central nervous system infections and control children. The two groups of children were compared in terms of the two indicators, and the diagnostic values of the two indicators were evaluated by ROC curve analysis. Results Children with viral encephalitis had significantly increased cerebrospinal concentrations of NPT and S100b compared with the control group and children with purulent meningitis (PPConclusions Both NPT and S100b have certain values in the diagnosis of central nervous system infections in children, and S100b is better than NPT.
ZHANG Li-Ya,LI Yan,JIN Mei-Fang. 383Diagnostic values of neopterin and S100b for central nervous system infections in children[J]. CJCP, 2014, 16(4): 380-383.
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