Abstract：Objective To investigate the role of Pediatric Critical Illness Score (PCIS) in evaluating the prognosis and severity of severe hand-foot-mouth disease (HFMD).Methods This study included 424 children with severe HFMD, consisting of 390 survivors and 34 deceased patients. Related physiological parameters and clinical data were collected for calculating PCIS scores. The area under receiver operating characteristic curve (AUC) was employed to assess the performance of PCIS in evaluating the complications and outcomes.Results The median of PCIS scores for survivors was higher than that for deceased patients (PCI) of PCIS was 0.74 (0.66, 0.82) in predicting pulmonary edema, 0.82 (0.74, 0.90) in predicting pulmonary hemorrhage, and 0.83 (0.75, 0.92) in predicting death.Conclusions PCIS can predict the complications and prognosis in children with severe HFMD. However, the existing scoring system of PCIS cannot fully assess the severity of HFMD.
LU Xiu-Lan,QIU Jun,ZHU Yi-Min et al. Role of Pediatric Critical Illness Score in evaluating severity and prognosis of severe hand-foot-mouth disease[J]. CJCP, 2015, 17(9): 961-964.
Wang C, Xie G, Cheng B, et al. Performance of pediatric risk of mortality, pediatric index of mortality and PIM2 in term Chinese neonates[J]. J Trop Pediatr, 2010, 56(4):235-241.
