Abstract：The increasing incidence rate of allergic diseases has attracted global attention, and these diseases greatly threaten children's health.The common pathogenesis of allergic diseases is the specific IgE-or cell-mediated immune response to common inhalant or food allergens.Epidemiological investigation, analysis of fecal flora, and clinical studies all suggest that the development and progression of allergic diseases are closely related to the early disturbance of intestinal flora.Probiotics can regulate intestinal immune response, increase the barrier function of epithelial cells, inhibit the adhesion and colonization of pathogenic bacteria, and thus restore or reconstruct normal intestinal flora.With the increasing understanding of allergic diseases, the effect of probiotics in the prevention and treatment of such diseases will be taken more and more seriously.
Houghteling PD, Walker WA. From birth to "immunohealth," allergies and enterocolitis[J]. J Clin Gastroenterol, 2015, 49 Suppl 1:S7-S12.
[2]
Matamoros S, Gras-Leguen C, Le Vacon F, et al. Development of intestinal microbiota in infants and its impact on health[J]. Trends Microbiol, 2013, 21(4):167-173.
[3]
Tang RB, Chang JK, Chen HL. Can probiotics be used to treat allergic diseases?[J]. J Chin Med Assoc, 2015, 78(3):154-157.
Aureli P, Capurso L, Castellazzi AM, et al. Probiotics and health:an evidence-based review[J]. Pharmacol Res, 2011, 63(5):366-376.
[6]
Qin J, Li R, Raes J, et al. A human gut microbial gene catalogue established by metagenomic sequencing[J]. Nature, 2010, 464(7285):59-65.
[7]
Dylag K, Hubalewska-Mazgaj M, Surmiak M, et al. Probiotics in the mechanism of protection against gut inflammation and therapy of gastrointestinal disorders[J]. Curr Pharm Des, 2014, 20(7):1149-1155.
Hwang JS, Im CR, Im SH. Immune disorders and its correlation with gut microbiome[J]. Immune Netw, 2012, 12(4):129-138.
[15]
Gaboriau-Routhiau V, Rakotobe S, Lécuyer E, et al. The key role of segmented filamentous bacteria in the coordinated maturation of gut helper T cell responses[J]. Immunity, 2009, 31(4):677-689.
[16]
Kwon HK, Lee CG, So JS, et al. Generation of regulatory dendritic cells and CD4+Foxp3+ T cells by probiotics administration suppresses immune disorders[J]. Proc Natl Acad Sci U S A, 2010, 107(5):2159-2164.
[17]
Bieber T. Atopic dermatitis[J]. N Engl J Med, 2008, 358(14):1483-1494.
[18]
Spergel JM. From atopic dermatitis to asthma:the atopic march[J]. Ann Allergy Asthma Immunol, 2010, 105(2):99-106.
[19]
McGowan EC, Keet CA. Prevalence of self-reported food allergy in the National Health and Nutrition Examination Survey(NHANES) 2007-2010[J]. J Allergy Clin Immunol, 2013, 132(5):1216-1219.
Compare D, Nardone G. The role of gut microbiota in the pathogenesis and management of allergic diseases[J]. Eur Rev Med Pharmacol Sci, 2013, 17(Suppl 2):11-17.
[31]
Tao B, Ruan G, Wang D, et al. Imbalance of peripheral Th17 and regulatory T cells in children with allergic rhinitis and bronchial asthma[J]. Iran J Allergy Asthma Immunol, 2015, 14(3):273-279.
Tollånes MC, Moster D, Daltveit AK, et al. Cesarean section and risk of severe childhood asthma:a population-based cohort study[J]. J Pediatr, 2008, 153(1):112-116.
[37]
Penders J, Thijs C, van den Brandt PA, et al. Gut microbiota composition and development of atopic manifestations in infancy:the KOALA Birth Cohort Study[J]. Gut, 2007, 56(5):661-667.
[38]
Vael C, Nelen V, Verhulst SL, et al. Early intestinal Bacteroides fragilis colonisation and development of asthma[J]. BMC Pulm Med, 2008, 8:19.
[39]
Yang SI, Lee E, Jung YH, et al. Effect of antibiotic use and mold exposure in infancy on allergic rhinitis in susceptible adolescents[J]. Ann Allergy Asthma Immunol, 2014, 113(2):160-165.
[40]
Ueno N, Fujiya M, Segawa S, et al. Heat-killed body of lactobacillus brevis SBC8803 ameliorates intestinal injury in a murine model of colitis by enhancing the intestinal barrier function[J]. Inflamm Bowel Dis, 2011, 17(11):2235-2250.
[41]
Kang HJ, Im SH. Probiotics as an Immune Modulator[J]. J Nutr Sci Vitaminol(Tokyo), 2015, 61 Suppl:S103-S105.
[42]
Żukiewicz-Sobczak W, Wróblewska P, Adamczuk P, et al. Probiotic lactic acid bacteria and their potential in the prevention and treatment of allergic diseases[J]. Cent Eur J Immunol, 2014, 39(1):104-108.
[43]
Madonini ER. Probiotics and allergies:myth or reality?[J]. Eur Ann Allergy Clin Immunol, 2014, 46(6):196-200.
Aureli P, Capurso L, Castellazzi AM, et al. Probiotics and health:an evidence-based review[J]. Pharmacol Res, 2011, 63(5):366-376.
[47]
Weiss G, Christensen HR, Zeuthen LH, et al. Lactobacilli and bifidobacteria induce differential interferonβ profiles in dendritic cells[J]. Cytokine, 2011, 56(2):520-530.
[48]
Elawadli I, Brisbin JT, Mallard BA, et al. Differential effects of lactobacilli on activation and maturation of mouse dendritic cells[J]. Benef Microbes, 2014, 5(3):323-334.
Kim HJ, Kim HY, Lee SY, et al. Clinical efficacy and mechanism of probiotics in allergic diseases[J]. Korean J Pediatr, 2013, 56(9):369-376.
[51]
Walker WA. Initial intestinal colonization in the human infant and immune homeostasis[J]. Ann Nutr Metab, 2013, 63 Suppl 2:8-15.
[52]
Huang J, Zhong Y, Cai W, et al. The effects of probiotics supplementation timing on an ovalbumin-sensitized rat model[J]. FEMS Immunol Med Microbiol, 2010, 60(2):132-141.
[53]
Isolauri E, Arvola T, Sütas Y, et al. Probiotics in the management of atopic eczema[J]. Clin Exp Allergy, 2000, 30(11):1604-1610.
[54]
Taibi A, Comelli EM. Practical approaches to probiotics use[J]. Appl Physiol Nutr Metab, 2014, 39(8):980-986.
[55]
Kimura G, Akagi H, Okada C, et al. Clinical effects of Lactobacillus acidophilus strain L-55-contained yogurt on symptoms of Japanese cedar pollen allergy[J]. Arerugi, 2012, 61(5):628-641.
[56]
Maldonado Galdeano C, Novotny Nuñez I, Carmuega E, et al. Role of probiotics and functional foods in health:gut immune stimulation by two probiotic strains and a potential probiotic yoghurt[J]. Endocr Metab Immune Disord Drug Targets, 2015, 15(1):37-45.
