Quality of life and its influencing factors in small for gestational age infants during early childhood
YANG Qin, ZHANG Xuan, CHENG Qian
Department of Health Care, Children's Hospital of Chongqing Medical University/Ministry of Education Key Laboratory of Child Development and Disorder/Chongqing Key Laboratory of Pediatrics/China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing 400014, China
Abstract:Objective To investigate the difference in quality of life (QOL) between small for gestational age (SGA) and appropriate for gestational age (AGA) infants during early childhood, and to investigate the factors influcing the QOL. Methods The Infant and Toddler Quality of Life Questionnaire-47 (ITQOL-SF47) was used to investigate the QOL of 1 to 3-year-old children born SGA and AGA who visited the child health care division. QOL was compared between SGA (n=203) and AGA groups (n=130), between the catch-up (n=119) and no-catch-up subgroups (n=84) of children born SGA, and between the single healthcare (n=144) and multiple healthcare subgroups (n=59) of children born SGA. The generalized linear model was used to investigate the factors influencing the QOL. Results The total ITQOL score of the SGA group was significantly lower than that of the AGA group (630±99 vs 716±84; PPPConclusions SGA infants have lower QOL than AGA infats during their early childhood. Proper promotion of catch-up growth and regular healthcare visits will contribute to the improvement of the QOL of SGA infants. The QOL of SGA infants is also influcenced by children's sex, residence and the degree of mothers' educational levels.
YANG Qin,ZHANG Xuan,CHENG Qian. Quality of life and its influencing factors in small for gestational age infants during early childhood[J]. CJCP, 2016, 18(4): 355-360.
Cianfarani S, Ladaki C, Geremia C. Hormonal regulation of postnatal growth in children born small for gestational age[J]. Horm Res, 2006, 65(Suppl 3): 70-74.
Ong KK, Ahmed ML, Emmett PM, et al. Association between postnatal catch-up growth and obesity in childhood: prospective cohort study[J]. BMJ, 2000, 320(7240): 967-971.
[6]
Landgraf JM. Measuring quality of life in pediatric enuresis: Precision and sensitivity of a new short-form for use in clinical care[J]. J Pediatr Urol, 2007, 3(2): 109-117.
[7]
Landgraf JM, Vogel I, Oostenbrink R, et al. Parent-reported health outcomes in infants/toddlers: measurement properties and clinical validity of the ITQOL-SF47[J]. Qual Life Res, 2013, 22(3): 635-646.
[8]
Spuijbroek AT, Oostenbrink R, Landgraf JM, et al. Health-related quality of life in preschool children in five health conditions[J]. Qual Life Res, 2011, 20(5): 779-786.
[9]
Stephen MD, Varni JW, Limbers CA, et al. Health-related quality of life and cognitive functioning in pediatric short stature: comparison of growth-hormone-naive, growth-hormone-treated, and healthy samples[J]. Eur J Pediatr, 2011, 170(3): 351-358.
Guellec I, Lapillonne A, Renolleau S, et al. Neurologic outcomes at school age in very preterm infants born with severe or mild growth restriction[J]. Pediatrics, 2011, 127(4): e883-e891.
[12]
Heinonen K, Räikkönen K, Pesonen AK, et al. Behavioural symptoms of attention deficit/hyperactivity disorder in preterm and term children born small and appropriate for gestational age: a longitudinal study[J]. BMC Pediatr, 2010, 10(1): 91.
Engle PL, Black MM, Behrman JR, et al. Strategies to avoid the loss of developmental potential in more than 200 million children in the developing world[J]. Lancet, 2007, 369(9557): 229-242.
[15]
Gianni ML, Picciolini O, Ravasi M, et al. The effects of an early developmental mother-child intervention program on neurodevelopment outcome in very low birth weight infants: a pilot study[J]. Early Hum Dev, 2006, 82(10): 691-695.