Abstract：Objective To investigate the nutritional risk in children with severe pneumonia using the Screening Tool for the Assessment of Malnutrition in Paediatrics (STAMP) and the association between nutritional risk and adverse clinical outcomes. Methods According to the STAMP score, 216 children with severe pneumonia were classified into high nutritional risk group (HR group; n=98), moderate nutritional risk group (MR group; n=65), and low nutritional risk group (LR group; n=53). Fasting blood samples were collected to measure the levels of insulin-like growth factor-1 (IGF-1), adiponectin, leptin, non-esterified fatty acid (NEFA), albumin, transferrin, prealbumin, and retinol binding protein (RBP). The adverse clinical outcomes were recorded. Results Compared with the MR and LR groups, the HR group had significantly lower serum levels of IGF-1, leptin, adiponectin, prealbumin, and RBP, as well as a significantly higher serum level of NEFA (P < 0.05). Compared with the MR and LR groups, the HR group had a significantly higher proportion of children admitted to the intensive care unit and a significantly longer duration of mechanical ventilation (P < 0.05). The HR group had a significantly longer mean hospital stay and a significantly higher incidence rate of complications compared with the LR and MR groups (P < 0.05). Conclusions Nutritional risk screening has an important value in evaluating the clinical outcome of children with severe pneumonia, and children at a higher nutritional risk tend to have more adverse clinical outcomes.
GUO Xiao-Hui,SUN Yan-Feng,WANG Jiang-Bo et al. Value of nutritional risk screening in evaluating adverse clinical outcomes in children with severe pneumonia[J]. CJCP, 2017, 19(3): 322-326.
Chourdakis M, Hecht C, Gerasimidis K, et al. Malnutrition risk in hospitalized children:use of 3 screening tools in a large European population[J]. Am J Clin Nutr, 2016, 103(5):1301-1310.
[7]
Moeeni V, Walls T, Day AS. Nutritional status and nutrition risk screening in hospitalized children in New Zealand[J]. Acta Paediatr, 2013, 102(9):e419-e423.
[8]
Teixeira AF, Viana KD. Nutritional screening in hospitalized pediatric patients:a systematic review[J]. J Pediatr (Rio J), 2016, 92(4):343-352.
Diener A, Rohrmann S. Associations of serum carotenoid concentrations and fruit or vegetable consumption with serum insulin-like growth factor (IGF)-1 and IGF binding protein-3 concentrations in the Third National Health and Nutrition Examination Survey (NHANES III)[J]. J Nutr Sci, 2016, 5:e13.
[14]
Bartz S, Mody A, Hornik C, et al. Severe acute malnutrition in childhood:hormonal and metabolic status at presentation, response to treatment, and predictors of mortality[J]. J Clin Endocrinol Metab, 2014, 99(6):2128-2137.
[15]
Chisti MJ, Salam MA, Bardhan PK, et al. Treatment failure and mortality amongst children with severe acute malnutrition presenting with cough or respiratory difficulty and radiological pneumonia[J]. PLoS One, 2015, 10(10):e0140327.
