Abstract：Objective To explore the recognition ability and abnormal processing characteristics to basic emotional faces in the early phase in children with autism spectrum disorders (ASD).Methods Photos of Chinese static faces with four basic emotions (fearful, happy, angry and sad) were used as stimulus. Twenty-five ASD children and twenty-two age-and gender-matched typical developed children (normal controls) were asked to match the emotional faces with words. Event-related potential (ERP) data were recorded concurrently.Results N170 latencies for total emotion and fearful face in the left temporal region were faster than in the right one in normal controls (P < 0.05), but the results were not noted in ASD children. Further, N170 latencies in the left temporal region of ASD children were slower than normal controls for total emotion, fearful and happy faces (P < 0.05), and their N170 latencies in the right temporal region were prone to slower than normal controls for angry and fearful faces.Conclusions The holistic perception speed of emotional faces in the early cognitive processing phase in ASD children is slower than normal controls. The lateralized response in the early phase of recognizing emotional faces may be aberrant in children with ASD.
LIN Qiong-Xi,WU Gui-Hua,ZHANG Ling et al. Abnormal processing characteristics to basic emotional faces in the early phase in children with autism spectrum disorder[J]. CJCP, 2018, 20(2): 134-139.
Huerta M, Bishop SL, Duncan A, et al. Application of DSM-5 criteria for autism spectrum disorder to three samples of children with DSM-IV diagnoses of pervasive developmental disorders[J]. Am J Psychiatry, 2012, 169(10):1056-1064.
[2]
Williams BT, Gray KM. The relationship between emotion recognition ability and social skills in young children with autism[J]. Autism, 2013, 17(6):762-768.
[3]
Pierce K, Redcay E. Fusiform function in children with an autism spectrum disorder is a matter of "who"[J]. Biol Psychiatry, 2008, 64(7):552-560.
[4]
Neuhaus E, Jones EJ, Barnes K, et al. The relationship between early neural responses to emotional faces at age 3 and later autism and anxiety symptoms in adolescents with autism[J]. J Autism Dev Disord, 2016, 46(7):2450-2463.
[5]
Tseng A, Wang Z, Huo Y, et al. Differences in neural activity when processing emotional arousal and valence in autism spectrum disorders[J]. Hum Brain Mapp, 2016, 37(2):443-461.
[6]
赵仑. ERPs实验教程[M]. 南京:东南大学出版社, 2010:20-44.
[7]
Harms MB, Martin A, Wallace GL. Facial emotion recognition in autism spectrum disorders:a review of behavioral and neuroimaging studies[J]. Neuropsychol Rev, 2010, 20(3):290-322.
[8]
Uljarevic M, Hamilton A. Recognition of emotions in autism:a formal meta-analysis[J]. J Autism Dev Disord, 2013, 43(7):1517-1526.
Tracy JL, Robins RW, Schriber RA, et al. Is emotion recognition impaired in individuals with autism spectrum disorders?[J]. J Autism Dev Disord, 2011, 41(1):102-109.
[11]
Fink E, de Rosnay M, Wierda M, et al. Brief report:accuracy and response time for the recognition of facial emotions in a large sample of children with autism spectrum disorders[J]. J Autism Dev Disord, 2014, 44(9):2363-2368.
[12]
Griffiths S, Jarrold C, Penton-Voak IS, et al. Impaired recognition of basic emotions from facial expressions in young people with autism spectrum disorder:assessing the importance of expression intensity[J]. J Autism Dev Disord, 2017:1-11.
[13]
Dyck MJ, Piek JP, Hay D, et al. Are abilities abnormally interdependent in children with autism?[J]. J Clin Child Adolesc, 2006, 35(1):20-33.
[14]
Braverman M, Fein D, Lucci D, et al. Affect comprehension in children with pervasive developmental disorders[J]. J Autism Dev Disord, 1989, 19(2):301-316.
[15]
Ozonoff S, Pennington BF, Rogers SJ. Are there emotion perception deficits in young autistic children?[J]. J Child Psychol Psyc, 1990, 31(3):343-361.
[16]
Rutherford MD, Troje NF. IQ predicts biological motion perception in autism spectrum disorders[J]. J Autism Dev Disord, 2012, 42(4):557-565.
[17]
Rump KM, Giovannelli JL, Minshew NJ, et al. The development of emotion recognition in individuals with autism[J]. Child Dev, 2009, 80(5):1434-1447.
[18]
Harms MB, Martin A, Wallace GL. Facial emotion recognition in autism spectrum disorders:a review of behavioral and neuroimaging studies[J]. Neuropsychol Rev, 2010, 20(3):290-322.
[19]
Eimer M. Event-related brain potentials distinguish processing stages involved in face perception and recognition[J]. Clin Neurophysiol, 2000, 111(4):694-705.
[20]
Batty M, Meaux E, Wittemeyer K, et al. Early processing of emotional faces in children with autism:An event-related potential study[J]. J Exp Child Psychol, 2011, 109(4):430-444.
[21]
Wong TK, Fung PC, Chua SE, et al. Abnormal spatiotemporal processing of emotional facial expressions in childhood autism:dipole source analysis of event-related potentials[J]. Eur J Neurosci, 2008, 28(2):407-416.
[22]
Apicella F, Sicca F, Federico RR, et al. Fusiform gyrus responses to neutral and emotional faces in children with autism spectrum disorders:a high density ERP study[J]. Behav Brain Res, 2013, 251:155-162.
[23]
Polk TA, Stallcup M, Aguirre GK, et al. Neural specialization for letter recognition[J]. J Cogn Neurosci, 2002, 14(2):145-159.
[24]
Bentin S, Allison T, Puce A, et al. Electrophysiological studies of face perception in humans[J]. J Cogn Neurosci, 1996, 8(6):551-565.
Curby KM, Willenbockel V, Tanaka JW, et al. Face processing in autism:insights from the perceptual expertise framework[M]//Gauthier I, Tarr MJ. Perceptual Expertise:Bridging Brain and Behavior. New York:Oxford University Press, 2010:139-166.
