15月龄女孩反复皮肤水疱7月余

李珂瑶; 汤建萍; 梁晓婷; 赵周英; 岳淑珍

doi:10.7499/j.issn.1008-8830.2019.09.015

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中国当代儿科杂志 ›› 2019, Vol. 21 ›› Issue (9) : 919-923. DOI: 10.7499/j.issn.1008-8830.2019.09.015

论著·病例分析

15月龄女孩反复皮肤水疱7月余

李珂瑶¹, 汤建萍¹, 梁晓婷¹, 赵周英², 岳淑珍¹

作者信息 +

Recurrent skin blisters for more than 7 months in a girl aged 15 months

LI Ke-Yao¹, TANG Jian-Ping¹, LIANG Xiao-Ting¹, ZHAO Zhou-Ying², YUE Shu-Zhen¹

Author information +

文章历史 +

摘要

患儿，女，15个月，因皮肤反复红斑、水疱和脱屑7月余就诊。吉姆萨染色及免疫组化染色显示肥大细胞浸润并伴有脱颗粒现象；苏木精-伊红染色镜下可见棘层水肿，表皮下水疱形成，疱内可见较多浆液及少量炎症细胞；真皮明显水肿，可见弥散的单一核细胞浸润。患儿确诊为肥大细胞增生症。对于皮肤反复红斑并伴有水疱的患儿，应考虑肥大细胞增生症的可能。

Abstract

A girl, aged 15 months, attended the hospital due to recurrent skin erythema, blisters, and desquamation for more than 7 months. Giemsa staining and immunohistochemical staining showed mast cell infiltration and degranulation. Hematoxylin staining showed spinous layer edema and blister formation under the epidermis, with a large amount of serous fluid and a small number of inflammatory cells in the blister. Marked edema was observed in the dermis, with diffused mononuclear cell infiltration. The girl was diagnosed with mastocytosis. Mastocytosis should be considered for children with recurrent skin erythema and blisters.

导出引用

李珂瑶, 汤建萍, 梁晓婷, 赵周英, 岳淑珍. 15月龄女孩反复皮肤水疱7月余[J]. 中国当代儿科杂志. 2019, 21(9): 919-923 https://doi.org/10.7499/j.issn.1008-8830.2019.09.015

LI Ke-Yao, TANG Jian-Ping, LIANG Xiao-Ting, ZHAO Zhou-Ying, YUE Shu-Zhen. Recurrent skin blisters for more than 7 months in a girl aged 15 months[J]. Chinese Journal of Contemporary Pediatrics. 2019, 21(9): 919-923 https://doi.org/10.7499/j.issn.1008-8830.2019.09.015

参考文献

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