Research advances in the effect of environmental stress in the neonatal intensive care unit on the neurodevelopment of preterm infants and its epigenetics
YUE Shao-Ting, ZHANG Jun, MA Deng-Hui
Department of Nursing, Wuhan University School of Health Sciences, Wuhan 430071, China
Abstract：Adverse environmental stimulation in the neonatal intensive care unit (NICU) can affect neurodevelopment through epigenetic modification and thus has adverse effects on the long-term developmental outcome of preterm infants. Developmental care can reverse epigenetic changes in genes and promote neurodevelopment in preterm infants. This article reviews the influence of environmental stress in the NICU and developmental care on neurodevelopment in preterm infants, as well as related epigenetic effects, in order to provide a reference for epigenetic studies of preterm infants.
YUE Shao-Ting,ZHANG Jun,MA Deng-Hui. Research advances in the effect of environmental stress in the neonatal intensive care unit on the neurodevelopment of preterm infants and its epigenetics[J]. CJCP, 2019, 21(11): 1144-1147.
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