Abstract：This paper is a comment on "Recommendation on the diagnosis and the use of antibiotics for early-onset sepsis in preterm infants:consensus of the expert panel from Hunan Province"[Chinese J Contemp Pediatr, 2020, 22(1):1-6]. This consensus offers suggestions for the diagnosis and antibiotic therapy of early-onset sepsis (EOS) in preterm infants in Hunan Province, which is of great significance for reducing unreasonable and unnecessary use of antibiotics. Based on this consensus, this comment discusses the diagnosis of EOS and the use of antibiotics in preterm infants.
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