Research advances in the effect of bioactive substances in breast milk on the growth and development of infants
ZHANG Meng, LI Wen-Xing, TANG Jun
Department of Pediatrics, West China Second University Hospital, Sichuan University/Key Laboratory of Birth Defects and Related Diseases of Women and Children(Sichuan University), Ministry of Education, Chengdu 610041, China
Abstract：There are various types of bioactive substances in human breast milk, such as active proteins, growth factors, cytokines, oligosaccharides, probiotics and cells. Many studies have shown that these bioactive substances in breast milk have important protective effects on infant growth and development, including anti-bacterial and anti-viral effects and the promotion of infant growth and development and immunologic maturation. They can also reduce the incidence rate of infectious diseases in infants, improve neural development in preterm infants, and reduce the risk of obesity and diabetes in future. However, there is still no clinical evidence for the effects of several active substances in breast milk, and their immunoregulatory mechanism remains unclear. Therefore, further studies are needed for clarification.
ZHANG Meng,LI Wen-Xing,TANG Jun. Research advances in the effect of bioactive substances in breast milk on the growth and development of infants[J]. CJCP, 2020, 22(1): 82-87.
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