昆明市5~14岁儿童肺通气功能参数实测值与Zap

doi:10.7499/j.issn.1008-8830.2007185

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摘要

目的研究昆明市5~14岁健康儿童肺通气功能主要参数实测值占Zapletal方程式预计值的百分比，为临床准确判断肺通气功能提供依据。方法纳入昆明市5~14岁健康儿童702名，其中男352名，女350名。采用Jaeger肺功能仪测定用力肺活量（FVC）、第1秒用力呼气容积（FEV1）、1秒率（FEV1/FVC）、最大中期呼气流量（MMEF）、用力呼气25%肺活量时瞬时流量（FEF25）、用力呼气50%肺活量时瞬时流量（FEF50）、用力呼气75%肺活量时瞬时流量（FEF75）、最高呼气流量（PEF）、每分钟最大通气量（MVV），共9项指标，以肺功能仪中提供的Zalpetal预计值公式得出的数值作为所选择儿童的预计值，计算其实测值占预计值的百分比。结果在702名儿童中，肺通气功能主要参数PEF、FVC、FEV1、FEV1/FVC、MVV实测值占预计值百分比的均值分别波动于102%~114%、94%~108%、98%~113%、98%~107%、141%~183%。气道流速指标功能参数FEF25、FEF50、FEF75、MMEF实测值占预计值百分比分别波动于98%~116%、85%~102%、71%~98%、83%~100%。各参数PEF、FVC、FEV1、FEV1/FVC、MVV、FEF25、FEF50、FEF75、MMEF实测值占Zapletal方程式预计值百分比的下限分别为88.2%、88.4%、92.0%、94.4%、118.5%、82.9%、70.0%、62.1%、70.1%。结论昆明地区5~14岁健康儿童肺通气功能参数水平与Zapletal方程式提供的正常值存在一定差异；该地区此年龄段的健康儿童肺通气功能参数PEF、FVC、FEV、FEV1/FVC、MVV、FEF25、FEF50、FEF75、MMEF实测值占预计值百分比的正常参考值下限可考虑分别设为88.2%、88.4%、92.0%、94.4%、118.5%、82.9%、70.0%、62.1%、70.1%。

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关键词 ：肺通气功能参数, 正常值下限, 昆明, 儿童

Abstract：Objective To study the percentage of the measured values of the main pulmonary ventilation function parameters in their predicted values based on Zapletal equation among healthy children aged 5-14 years in Kunming, China, and to provide a basis for accurate judgment of pulmonary ventilation function in clinical practice. Methods A total of 702 healthy children aged 5-14 years (352 boys and 350 girls) from Kunming were enrolled. The Jaeger spirometer was used to measure the nine indices:forced vital capacity (FVC), forced expiratory volume in one second (FEV1), ratio of forced expiratory volume in one second to forced vital capacity (FEV1/FVC), maximal mid-expiratory flow (MMEF), forced expiratory flow at 25% of forced vital capacity (FEF25), forced expiratory flow at 50% of forced vital capacity (FEF50), forced expiratory flow at 75% of forced vital capacity (FEF75), peak expiratory flow (PEF), and maximal voluntary ventilation (MVV). The values obtained from the Zapletal equation of predicted values provided by the spirometer were used as the predicted values of children, and the percentage of measured values in predicted values was calculated. Results In the 702 children, the percentages of the measured values of the main pulmonary ventilation function parameters PEF, FVC, FEV1, FEV1/FVC, and MVV in their predicted values fluctuated from 102% to 114%, 94% to 108%, 98% to 113%, 98% to 107%, and 141% to 183% respectively. As for the main airway velocity parameters, the percentages of the measured values of FEF25, FEF50, FEF75, and MMEF in their predicted values fluctuated from 98% to 116%, 85% to 102%, 71% to 98%, and 83% to 100% respectively. The percentages of the measured values of PEF, FVC, FEV1, FEV1/FVC, MVV, FEF25, FEF50, FEF75, and MMEF in their predicted values had the lower limits of normal of 88.2%, 88.4%, 92.0%, 94.4%, 118.5%, 82.9%, 70.0%, 62.1%, and 70.1% respectively. Conclusions There are differences between pulmonary ventilation function parameter levels and normal values provided by Zapletal equation in healthy children aged 5-14 years in Kunming. As for the pulmonary ventilation function parameters of PEF, FVC, FEV, FEV1/FVC, MVV, FEF25, FEF50, FEF75, and MMEF in these children, the lower limits of normal of measured values in predicted values may be determined as 88.2%, 88.4%, 92.0%, 94.4%, 118.5%, 82.9%, 70.0%, 62.1%, and 70.1% respectively.

Key words： Pulmonary ventilation function parameter Lower limit of normal Kunming Child

收稿日期: 2020-07-27

作者简介: 杨洁,女,学士,副主任医师。Email:yangjiehk75@sina.com。

引用本文:

杨洁,付红敏,白涛珍等. 昆明市5~14岁儿童肺通气功能参数实测值与Zap[J]. 中国当代儿科杂志, 2020, 22(12): 1313-1319.

YANG Jie,FU Hong-Min,BAI Tao-Zhen et al. Pulmonary ventilation function parameters of children aged 5-14 years in Kunming, China: a comparative analysis of measured values versus predicted values based on Zapletal equation[J]. CJCP, 2020, 22(12): 1313-1319.

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http://www.zgddek.com/CN/10.7499/j.issn.1008-8830.2007185 或 http://www.zgddek.com/CN/Y2020/V22/I12/1313

[1]	冯雍, 张皓, 尚云晓. 我国儿童肺功能的发展历程及展望[J]. 国际儿科学杂志, 2019, 46(9):617-621.
[2]	皇惠杰, 向莉. 儿童气道过敏性疾病中肺通气功能检测临床应用的研究进展[J]. 国际儿科学杂志, 2018, 45(3):188-191.
[3]	李硕, 宋欣, 刘传合, 等. 北京市5~14岁儿童肺通气功能正常值的测定[J]. 中华实用儿科临床杂志, 2013, 28(17):1343-1346.
[4]	陆燕红, 杨晓蕴, 郝创利. 苏州市区儿童肺通气功能正常值及预测值方程式的建立[J]. 临床儿科杂志, 2012, 30(8):716-720.
[5]	张洁妍, 潘志伟, 刘志刚, 等. 佛山市禅城区5~14岁儿童肺通气功能正常预计值研究[J]. 中国妇幼保健, 2020, 35(3):476-479.
[6]	Langhammer A, Johannessen A, Holmen TL, et al. Global Lung Function Initiative 2012 reference equations for spirometry in the Norwegian population[J]. Eur Respir J, 2016, 48(6):1602-1611.
[7]	丁敏, 潘家华, 计明红, 等. 合肥市学龄期健康儿童肺功能正常值测定及影响因素分析[J]. 临床肺科杂志, 2019, 24(8):1410-1414.
[8]	郑劲平. 我国肺功能检测应用现状的调查和分析[J]. 中华结核和呼吸杂志, 2002, 25(2):69-73.
[9]	Quanjer PH, Stanojevic S, Cole TJ, et al. Multi-ethnic reference values for spirometry for the 3-95-yr age range:the global lung function 2012 equations[J]. Eur Respir J, 2012, 40(6):1324-1343.
[10]	Derom E, Liistro G, Oostveen E, et al. Launching Global Lung Function Initiative reference values in Belgium:tips and tricks[J]. Eur Respir J, 2018, 52(2):1800922.
[11]	张皓, 邬宇芬, 黄剑峰, 等. 儿童肺功能检测及评估专家共识[J]. 临床儿科杂志, 2014, 32(2):104-114.
[12]	中华医学会儿科学分会呼吸学组肺功能协作组, 《中华实用儿科临床杂志》编辑委员会. 儿童肺功能系列指南(二):肺容积和通气功能[J]. 中华实用儿科临床杂志, 2016, 31(10):744-750.
[13]	Global Initiative for Asthma. 2019 GINA Report, Global Strategy for Asthma Management and Prevention[EB/OL].[2020-06-30]. https://ginasthma.org/reports/2019-gina-report-global-strategy-for-asthma-management-and-prevention/.
[14]	张晶鑫, 刘传合, 李硕, 等. 1秒率作为患儿气道阻塞判断标准的界值选取[J]. 中华儿科杂志, 2020, 58(2):140-144.
[15]	刘传合, 李硕. 用力呼气肺功能在儿科临床应用中的几个问题[J]. 中华实用儿科临床杂志, 2020, 35(4):258-262.
[16]	宋欣, 赵梦雅, 杨哲, 等. 北京地区5~14岁健康儿童肺通气功能参数实测值占预计值百分比研究[J]. 中华实用儿科临床杂志, 2017, 32(11):848-851.
[17]	戴银芳, 孟宁, 王宇清, 等. 苏州农村儿童肺功能正常值及其相关因素分析[J]. 临床儿科杂志, 2019, 37(3):182-187.
[18]	廉建丽, 李继玲, 陈俊松. 小气道功能指标在儿童哮喘病情严重程度评估及临床诊断中的应用[J]. 安徽医药, 2019, 23(6):1101-1105.
[19]	陈俊松, 李敏, 汤昱. 小气道功能指标在儿童哮喘缓解期病情评估中的意义[J]. 浙江医学, 2018, 40(7):722-724.
[20]	Arshad SH, Kurukulaaratchy R, Zhang H, et al. Assessing small airway function for early detection of lung function impairment[J]. Eur Respir J, 2020, 56(1):2001946.
[21]	Quanjer PH, Brazzale DJ, Boros PW, et al. Implications of adopting the Global Lungs Initiative 2012 all-age reference equations for spirometry[J]. Eur Respir J, 2013, 42(4):1046-1054.
[22]	Quanjer PH, Weiner DJ. Interpretative consequences of adopting the Global Lungs 2012 reference equations for spirometry for children and adolescents[J]. Pediatr Pulmonol, 2014, 49(2):118-125.
[23]	Beydon N, Davis SD, Lombardi E, et al. An official American Thoracic Society/European Respiratory Society statement:pulmonary function testing in preschool children[J]. Am J Respir Crit Care Med, 2007, 175(12):1304-1345.
[24]	Pellegrino R, Viegi G, Brusasco V, et al. Interpretative strategies for lung function tests[J]. Eur Respir J, 2005, 26(5):948-968.