Interpretation of "Clinical Considerations for Monkeypox in Children and Adolescents" released by the US Centers for Disease Control and Prevention
YAO Kai-Hu
National Center for Children's Health/Beijing Children's Hospital, Capital Medical University/Laboratory of Dermatology, Beijing Pediatric Research Institute/National Key Discipline of Pediatrics (Capital Medical University)/Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing 100045, China
Abstract：In order to cope with monkeypox in children and adolescents, the US Centers for Disease Control and Prevention released "Clinical Considerations for Monkeypox in Children and Adolescents", which is specially written for pediatric health workers serving children and adolescents under the age of 18 years to standardize the clinical management of children and adolescents with exposure to monkeypox (human monkeypox or animal monkeypox) or with suspected or confirmed monkeypox. This document highlights the characteristics of children and adolescents and gives some valuable suggestions to the special issues in pediatric clinical practice, and it is worth studying by pediatric health workers who are preparing for a possible epidemic of monkeypox.
YAO Kai-Hu. Interpretation of "Clinical Considerations for Monkeypox in Children and Adolescents" released by the US Centers for Disease Control and Prevention[J]. CJCP, 2022, 24(10): 1078-1084.
1 World Health Organization. WHO Director-General's statement at the press conference following IHR Emergency Committee regarding the multi-country outbreak of monkeypox-23 July 2022[EB/OL]. (2022-07-23)[2022-07-26]. https://www.who.int/director-general/speeches/detail/who-director-general-s-statement-on-the-press-conference-following-IHR-emergency-committee-regarding-the-multi--country-outbreak-of-monkeypox--23-july-2022.
2 Burki T. What does it mean to declare monkeypox a PHEIC?[J]. Lancet Infect Dis, 2022. Epub ahead of print. PMID: 35964617. DOI: 10.1016/S1473-3099(22)00540-0.
Jezek Z, Szczeniowski M, Paluku KM, et al. Human monkeypox: clinical features of 282 patients[J]. J Infect Dis, 1987, 156(2): 293-298. PMID: 3036967. DOI: 10.1093/infdis/156.2.293.
5 Centers for Disease Control and Prevention. Clinical considerations for monkeypox in children and adolescents[EB/OL]. (2022-08-22)[2022-08-30]. https://www.cdc.gov/poxvirus/monkeypox/clinicians/pediatric.html.
6 Centers for Disease Control and Prevention. 2022 monkeypox outbreak global map[EB/OL]. (2022-08-19)[2022-08-20]. https://www.cdc.gov/poxvirus/monkeypox/response/2022/world-map.html.
7 World Health Organization European Region. Joint ECDC-WHO regional office for Europe monkeypox surveillance bulletin[EB/OL]. (2022-08-17)[2022-08-19]. https://monkeypoxreport.ecdc.europa.eu/.
10 World Health Organization. Multi-country monkeypox outbreak: situation update[EB/OL]. (2022-06-27)[2022-07-15]. https://www.who.int/emergencies/disease-outbreak-news/item/2022-DON396.
Guagliardo SAJ, Monroe B, Moundjoa C, et al. Asymptomatic Orthopoxvirus circulation in humans in the wake of a monkeypox outbreak among chimpanzees in Cameroon[J]. Am J Trop Med Hyg, 2020, 102(1): 206-212. PMID: 31769389. PMCID: PMC6947779. DOI: 10.4269/ajtmh.19-0467.
Patel A, Bilinska J, Tam JCH, et al. Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series[J]. BMJ, 2022, 378: e072410. PMID: 35902115. PMCID: PMC9331915. DOI: 10.1136/bmj-2022-072410.
Petersen E, Kantele A, Koopmans M, et al. Human monkeypox: epidemiologic and clinical characteristics, diagnosis, and prevention[J]. Infect Dis Clin North Am, 2019, 33(4): 1027-1043. PMID: 30981594. DOI: 10.1016/j.idc.2019.03.001.
16 Centers for Disease Control and Prevention. Treatment information for healthcare professionals[EB/OL]. (2022-07-28)[2022-08-16]. https://www.cdc.gov/poxvirus/monkeypox/clinicians/treatment.html.
19 World Health Organization. Vaccines and immunization for monkeypox: interim guidance, 14 June 2022[EB/OL]. (2022-06-14)[2022-08-16]. https://www.who.int/publications/i/item/who-mpx-immunization-2022.1.
20 Centers for Disease Control and Prevention. Infection prevention and control of monkeypox in healthcare settings[EB/OL]. (2022-08-11)[2022-08-18]. https://www.cdc.gov/poxvirus/monkeypox/clinicians/infection-control-healthcare.html.
21 Centers for Disease Control and Prevention. Isolation and infection control at home[EB/OL]. (2022-08-11)[2022-08-18]. https://www.cdc.gov/poxvirus/monkeypox/clinicians/infection-control-home.html.
22 Seang S, Burrel S, Todesco E, et al. Evidence of human-to-dog transmission of monkeypox virus[J]. Lancet, 2022. Epub ahead of print. PMID: 35963267. DOI: 10.1016/S0140-6736(22)01487-8.
23 Centers for Disease Control and Prevention. Clinical considerations for monkeypox in people who are pregnant or breastfeeding[EB/OL]. (2022-07-18)[2022-08-18]. https://www.cdc.gov/poxvirus/monkeypox/clinicians/pregnancy.html.
Anderson MG, Frenkel LD, Homann S, et al. A case of severe monkeypox virus disease in an American child: emerging infections and changing professional values[J]. Pediatr Infect Dis J, 2003, 22(12): 1093-1096. PMID: 14688573. DOI: 10.1097/01.inf.0000101821.61387.a5.
