Safety of modified T-piece resuscitator versus nasal cannula oxygen in electronic bronchoscopy for infants: a prospective randomized controlled study
NING Jun-Jie, ZUO Zhi-Hui, YU Zhi-Dong, LI Xue-Mei, QIAO Li-Na
Pediatric Intensive Care Unit, West China Second University Hospital, Sichuan University, Chengdu 610041, China; National Health Commission Key Laboratory of Chronobiology (Sichuan University), Chengdu 610041, China; Key Laboratory of Birth Defects and Related Diseases of Women and Children, Chengdu 610041, China (Qiao L-N, Email: qiaolina@scu.edu.cn)
Abstract：Objective To optimize the oxygen therapy regimens for infants with pulmonary diseases during bronchoscopy. Methods A prospective randomized, controlled, and single-center clinical trial was conducted on 42 infants who underwent electronic bronchoscopy from July 2019 to July 2021. These infants were divided into a nasal cannula (NC) group and a modified T-piece resuscitator (TPR) group using a random number table. The lowest intraoperative blood oxygen saturation was recorded as the primary outcome, and intraoperative heart rate and respiratory results were recorded as the secondary outcomes. Results Compared with the NC group, the modified TPR group had a significantly higher level of minimum oxygen saturation during surgery and a significantly lower incidence rate of hypoxemia (P<0.05). In the modified TPR group, there were 6 infants with mild hypoxemia, 2 with moderate hypoxemia, and 1 with severe hypoxemia, while in the NC group, there were 3 infants with mild hypoxemia, 5 with moderate hypoxemia, and 9 with severe hypoxemia (P<0.05). The modified TPR group had a significantly lower incidence rate of intraoperative respiratory rhythm abnormalities than the NC group (P<0.05), but there was no significant difference in the incidence rate of arrhythmias between the two groups (P>0.05). Conclusions Modified TPR can significantly reduce the risk of hypoxemia in infants with pulmonary diseases during electronic bronchoscopy, and TPR significantly decreases the severity of hypoxemia and the incidence of respiratory rhythm abnormalities compared with traditional NC.
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