虚拟现实技术在孤独症谱系障碍儿童干预中的研究进展

doi:10.7499/j.issn.1008-8830.2310142

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摘要孤独症谱系障碍（autism spectrum disorder, ASD）是儿童期神经发育障碍性疾病之一，目前治疗尚无特效方法，主要干预措施以教育训练和行为矫正为主。虚拟现实作为新兴技术，是一种以计算机为基础的环境模拟系统，通过融合多种来源信息实现交互式动态和沉浸式体验，近年逐渐被应用于ASD儿童干预训练。该文将综述虚拟现实在ASD儿童的情绪认知、社交能力、生活能力、运动能力、特殊恐惧方面的干预研究进展，为ASD干预训练拓展新方向。

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	郭乃绮
	王瑜

关键词 ：孤独症谱系障碍, 虚拟现实, 干预, 儿童

Abstract：Autism spectrum disorder (ASD) is one of the neurodevelopmental disorders in children, and there are currently no specific treatments, with the main interventions focusing on educational training and behavioral correction. Virtual reality, as an emerging technology, is a computer-based environmental simulation system that achieves interactive dynamics and immersive experiences by integrating information from multiple sources. In recent years, it has been gradually applied in intervention training for children with ASD. This paper reviews the recent studies on the effects of virtual reality intervention on emotional cognition, social skills, daily living skills, motor skills, and specific phobias in children with ASD, offering a new direction for ASD intervention training.

Key words： Autism spectrum disorder Virtual reality Intervention Child

收稿日期: 2023-10-30

基金资助:上海交通大学/医学院-儿童医院临床研究培育专项重点项目（2021YLYZ02）；上海市卫生健康委员会公共卫生体系建设三年行动计划（2020—2022年）重点学科建设项目（GWV-10.1-XK14）；深圳市深爱公益基金会专项研究基金（SA202300107）；上海交通大学医学院-儿童医院临床研究培育专项面上项目（2022YLYM09）。

通讯作者: 王瑜，女，主任医师。Email：wy_rain@126.com。 E-mail: wy_rain@126.com

作者简介: 郭乃绮，女，硕士研究生；

引用本文:

郭乃绮,王瑜. 虚拟现实技术在孤独症谱系障碍儿童干预中的研究进展[J]. 中国当代儿科杂志, 2024, 26(4): 414-419.

KUO Nai-Chi,WANG Yu. Recent advances in the virtual reality technology for treating children with autism spectrum disorder[J]. CJCP, 2024, 26(4): 414-419.

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http://www.zgddek.com/CN/10.7499/j.issn.1008-8830.2310142 或 http://www.zgddek.com/CN/Y2024/V26/I4/414

	1 American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders[M]. 5th ed. Arlington, VA: American Psychiatric Association, 2013: 591-643.
	Maenner MJ, Warren Z, Williams AR, et al. Prevalence and characteristics of autism spectrum disorder among children aged 8 years: Autism and Developmental Disabilities Monitoring Network, 11 sites, United States, 2020[J]. MMWR Surveill Summ, 2023, 72(2): 1-14. PMID: 36952288. PMCID: PMC10042614. DOI: 10.15585/mmwr.ss7202a1.
	Zhou H, Xu X, Yan W, et al. Prevalence of autism spectrum disorder in China: a nationwide multi-center population-based study among children aged 6 to 12 years[J]. Neurosci Bull, 2020, 36(9): 961-971. PMID: 32607739. PMCID: PMC7475160. DOI: 10.1007/s12264-020-00530-6.
	Hyman SL, Levy SE, Myers SM, et al. Identification, evaluation, and management of children with autism spectrum disorder[J]. Pediatrics, 2020, 145(1): e20193447. PMID: 31843864. DOI: 10.1542/peds.2019-3447.
	5 李海, 赵朔, 洪琦, 等. 孤独症谱系障碍儿童家长的家庭干预培训需求调查[J]. 中国康复医学杂志, 2023, 38(11): 1571-1575. DOI: 10.3969/j.issn.1001-1242.2023.11.014.
	Bertacchini F, Demarco F, Scuro C, et al. A social robot connected with chatGPT to improve cognitive functioning in ASD subjects[J]. Front Psychol, 2023, 14: 1232177. PMID: 37868599. PMCID: PMC10585023. DOI: 10.3389/fpsyg.2023.1232177.
	Shane HC, Albert PD. Electronic screen media for persons with autism spectrum disorders: results of a survey[J]. J Autism Dev Disord, 2008, 38(8): 1499-1508. PMID: 18293074. DOI: 10.1007/s10803-007-0527-5.
	Chen Q, Deister CA, Gao X, et al. Dysfunction of cortical GABAergic neurons leads to sensory hyper-reactivity in a Shank3 mouse model of ASD[J]. Nat Neurosci, 2020, 23(4): 520-532. PMID: 32123378. PMCID: PMC7131894. DOI: 10.1038/s41593-020-0598-6.
	Lee JH, Lee TS, Yoo SY, et al. Metaverse-based social skills training programme for children with autism spectrum disorder to improve social interaction ability: an open-label, single-centre, randomised controlled pilot trial[J]. EClinicalMedicine, 2023, 61: 102072. PMID: 37483546. PMCID: PMC10359727. DOI: 10.1016/j.eclinm.2023.102072.
	Yeung AWK, Tosevska A, Klager E, et al. Virtual and augmented reality applications in medicine: analysis of the scientific literature[J]. J Med Internet Res, 2021, 23(2): e25499. PMID: 33565986. PMCID: PMC7904394. DOI: 10.2196/25499.
	McCleery JP, Zitter A, Solórzano R, et al. Safety and feasibility of an immersive virtual reality intervention program for teaching police interaction skills to adolescents and adults with autism[J]. Autism Res, 2020, 13(8): 1418-1424. PMID: 32762029. DOI: 10.1002/aur.2352.
	12 Yazici MS, McKenzie B. Strategies used to develop socio-communicative skills among children with autism in a Turkish special education school and implications for development of practice[J]. Int J Disabil Dev Educ, 2020, 67(5): 515-535. DOI: 10.1080/1034912X.2019.1614152.
	13 Bian DY, Wade J, Swanson A, et al. Design of a physiology-based adaptive virtual reality driving platform for individuals with ASD[J]. ACM Trans Access Comput, 2019, 12(1): 2. DOI: 10.1145/3301498.
	Hocking DR, Ardalan A, Abu-Rayya HM, et al. Feasibility of a virtual reality-based exercise intervention and low-cost motion tracking method for estimation of motor proficiency in youth with autism spectrum disorder[J]. J Neuroeng Rehabil, 2022, 19(1): 1. PMID: 34996473. PMCID: PMC8742363. DOI: 10.1186/s12984-021-00978-1.
	Johnson CR, Barto L, Worley S, et al. Telehealth parent training for sleep disturbances in young children with autism spectrum disorder: a randomized controlled trial[J]. Sleep Med, 2023, 111: 208-219. PMID: 37806263. DOI: 10.1016/j.sleep.2023.08.033.
	Tavassoli T, Miller LJ, Schoen SA, et al. Sensory reactivity, empathizing and systemizing in autism spectrum conditions and sensory processing disorder[J]. Dev Cogn Neurosci, 2018, 29: 72-77. PMID: 28579480. PMCID: PMC6987900. DOI: 10.1016/j.dcn.2017.05.005.
	Berkovits L, Eisenhower A, Blacher J. Emotion regulation in young children with autism spectrum disorders[J]. J Autism Dev Disord, 2017, 47(1): 68-79. PMID: 27838805. DOI: 10.1007/s10803-016-2922-2.
	Goldsmith SF, Kelley E. Associations between emotion regulation and social impairment in children and adolescents with autism spectrum disorder[J]. J Autism Dev Disord, 2018, 48(6): 2164-2173. PMID: 29427118. DOI: 10.1007/s10803-018-3483-3.
	19 Ip HHS, Wong SWL, Chan DFY, et al. Enhance affective expression and social reciprocity for children with autism spectrum disorder: using virtual reality headsets at schools[J]. Interact Learn Environ, 2022. Epub ahead of print. DOI: 10.1080/10494820.2022.2107681.
	Chu L, Shen L, Ma C, et al. Effects of a nonwearable digital therapeutic intervention on preschoolers with autism spectrum disorder in China: open-label randomized controlled trial[J]. J Med Internet Res, 2023, 25: e45836. PMID: 37616029. PMCID: PMC10485722. DOI: 10.2196/45836.
	Neuhaus E, Webb SJ, Bernier RA. Linking social motivation with social skill: the role of emotion dysregulation in autism spectrum disorder[J]. Dev Psychopathol, 2019, 31(3): 931-943. PMID: 30957732. PMCID: PMC8148424. DOI: 10.1017/S0954579419000361.
	Ung D, Wood JJ, Ehrenreich-May J, et al. Clinical characteristics of high-functioning youth with autism spectrum disorder and anxiety[J]. Neuropsychiatry (London), 2013, 3(2): 10.2217/npy.13.9. PMID: 24179485. PMCID: PMC3808966. DOI: 10.2217/npy.13.9.
	Ke F, Moon J, Sokolikj Z. Designing and deploying a virtual social sandbox for autistic children[J]. Disabil Rehabil Assist Technol, 2022. Epub ahead of print. PMID: 36524469. DOI: 10.1080/17483107.2022.2156630.
	Soltiyeva A, Oliveira W, Madina A, et al. My lovely granny's farm: an immersive virtual reality training system for children with autism spectrum disorder[J]. Educ Inf Technol (Dordr), 2023, 28(12): 16887-16907. PMID: 37361850. PMCID: PMC10199436. DOI: 10.1007/s10639-023-11862-x.
	25 Lu A, Chan S, Cai YY, et al. Learning through VR gaming with virtual pink dolphins for children with ASD[J]. Interact Learn Environ, 2018, 26(6): 718-729. DOI: 10.1080/10494820.2017.1399149.
	Lee LC, Harrington RA, Chang JJ, et al. Increased risk of injury in children with developmental disabilities[J]. Res Dev Disabil, 2008, 29(3): 247-255. PMID: 17582739. DOI: 10.1016/j.ridd.2007.05.002.
	27 Tan QP, Huang LH, Xu D, et al. Serious game for VR road crossing in special needs education[J]. Electronics (Basel), 2022, 11(16): 2568. DOI: 10.3390/electronics11162568.
	Penton T, Bowling N, Vafeiadou A, et al. Attitudes to interpersonal touch in the workplace in autistic and non-autistic groups[J]. J Autism Dev Disord, 2023, 53(12): 4731-4743. PMID: 36083393. PMCID: PMC10627924. DOI: 10.1007/s10803-022-05710-z.
	29 Genova HM, Lancaster K, Morecraft J, et al. A pilot RCT of virtual reality job interview training in transition-age youth on the autism spectrum[J]. Res Autism Spectr Disord, 2021, 89: 101878. DOI: 10.1016/j.rasd.2021.101878.
	Kilroy E, Ring P, Hossain A, et al. Motor performance, praxis, and social skills in autism spectrum disorder and developmental coordination disorder[J]. Autism Res, 2022, 15(9): 1649-1664. PMID: 35785418. PMCID: PMC9543450. DOI: 10.1002/aur.2774.
	Moraes íAP, Lima JA, Silva NM, et al. Effect of longitudinal practice in real and virtual environments on motor performance, physical activity and enjoyment in people with autism spectrum disorder: a prospective randomized crossover controlled trial[J]. Int J Environ Res Public Health, 2022, 19(22): 14668. PMID: 36429386. PMCID: PMC9690405. DOI: 10.3390/ijerph192214668.
	32 He JL, Zhang HY, Zhao HY. Research on the auxiliary treatment system of childhood autism based on virtual reality[J]. J Decis Syst, 2021. Epub ahead of print. DOI: 10.1080/12460125.2021.2003512.
	Leyfer OT, Folstein SE, Bacalman S, et al. Comorbid psychiatric disorders in children with autism: interview development and rates of disorders[J]. J Autism Dev Disord, 2006, 36(7): 849-861. PMID: 16845581. DOI: 10.1007/s10803-006-0123-0.
	34 Stiegler LN, Davis R. Understanding sound sensitivity in individuals with autism spectrum disorders[J]. Focus Autism Other Dev Disabl, 2010, 25(2): 67-75. DOI: 10.1177/1088357610364530.
	35 Lucker JR. Auditory hypersensitivity in children with autism spectrum disorders[J]. Focus Autism Other Dev Disabl, 2013, 28(3): 184-191. DOI: 10.1177/1088357613475810.
	36 Johnston D, Egermann H, Kearney G. SoundFields: a virtual reality game designed to address auditory hypersensitivity in individuals with autism spectrum disorder[J]. Appl Sci, 2020, 10(9): 2996. DOI: 10.3390/app10092996.
	37 Maskey M, McConachie H, Rodgers J, et al. An intervention for fears and phobias in young people with autism spectrum disorders using flat screen computer-delivered virtual reality and cognitive behaviour therapy[J]. Res Autism Spectr Disord, 2019, 59: 58-67. DOI: 10.1016/j.rasd.2018.11.005.
	Oh H, Lee G. Feasibility of full immersive virtual reality video game on balance and cybersickness of healthy adolescents[J]. Neurosci Lett, 2021, 760: 136063. PMID: 34174345. DOI: 10.1016/j.neulet.2021.136063.
	39 Chen CY, Chuang CH, Tsai TL, et al. Reducing cybersickness by implementing texture blur in the virtual reality content[J]. Virtual Real, 2022, 26(2): 789-800. DOI: 10.1007/s10055-021-00587-2.
	Karami B, Koushki R, Arabgol F, et al. Effectiveness of virtual/augmented reality-based therapeutic interventions on individuals with autism spectrum disorder: a comprehensive meta-analysis[J]. Front Psychiatry, 2021, 12: 665326. PMID: 34248702. PMCID: PMC8260941. DOI: 10.3389/fpsyt.2021.665326.
	De Luca R, Naro A, Colucci PV, et al. Improvement of brain functional connectivity in autism spectrum disorder: an exploratory study on the potential use of virtual reality[J]. J Neural Transm (Vienna), 2021, 128(3): 371-380. PMID: 33677622. DOI: 10.1007/s00702-021-02321-3.
	42 Yang DW, Zhou J, Chen RC, et al. Expert consensus on the metaverse in medicine[J]. Clin eHealth, 2022, 5: 1-9. DOI: 10.1016/j.ceh.2022.02.001.