36株青少年幽门螺杆菌耐药分析

黄烈平, 庄满利, 顾承萍

中国当代儿科杂志 ›› 2009, Vol. 11 ›› Issue (03) : 210-212.

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中国当代儿科杂志 ›› 2009, Vol. 11 ›› Issue (03) : 210-212.
论著·临床研究

36株青少年幽门螺杆菌耐药分析

  • 黄烈平,庄满利,顾承萍
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Antimicrobial resistance of 36 strains of Helicobacter pylori in adolescents

  • HUANG Lie-Ping, ZHUANG Man-Li, GU Cheng-Ping
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摘要

目的:了解该地区青少年幽门螺杆菌(HP)常用抗菌药物的耐药性。方法:对108例青少年患者进行胃镜检查,并取胃黏膜标本1块进行HP培养分离,采用Kirby-Baner药敏纸片对培养分离到的菌株进行抗菌药物的敏感性试验。结果:108例中成功分离出HP菌株36例,对克拉霉素耐药率8.3%(3/36)、阿莫西林耐药率33.3%(12/36)、甲硝唑耐药率94.4%(34/36)、呋喃唑酮耐药率16.7%(6/36),而庆大霉素和左氧氟沙星均未检出耐药菌株。结论:该地区青少年HP对甲硝唑和阿莫西林耐药率较高,对克拉霉素和呋喃唑酮耐药率较低,而对庆大霉素和左氧氟沙星无耐药菌株。[中国当代儿科杂志,2009,11(3):210-212]

Abstract

OBJECTIVE: To investigate the resistance of Helicobacter pylori (H.pylori) to antimicrobial agents in adolescents. METHODS: One hundred and eight adolescents (6-18 years old) underwent a gastroscopy examination. H.pylori strains were isolated from gastric mucosa. Antimicrobial susceptibility testing was performed by means of Kirby-Baner. RESULTS: Thirty-six H.pylori strains were identified. The resistant rate of H.pylori strains to clarithromycin, fruranzolidone and amoxicillin was 8.3%, 16.7% and 33.3%, respectively. H.pylori strains showed a high resistance to metronidazole (94.4%), while no strain was resistant to gentamicin and levofloxacin. CONCLUSIONS:The H.pylori strains from the adolescents in Zhejiang showed a high resistance to metronidazole and amoxicillin but a low resistance to clarithromycin and fruranzolidone. All of H.pylori strains were susceptive to gentamicin and levofloxacin.[Chin J Contemp Pediatr, 2009, 11 (3):210-212]

关键词

幽门螺杆菌 / 药敏试验 / 耐药性 / 青少年

Key words

Helicobacter pylori / Susceptibility test / Resistance / Adolescent

引用本文

导出引用
黄烈平, 庄满利, 顾承萍. 36株青少年幽门螺杆菌耐药分析[J]. 中国当代儿科杂志. 2009, 11(03): 210-212
HUANG Lie-Ping, ZHUANG Man-Li, GU Cheng-Ping. Antimicrobial resistance of 36 strains of Helicobacter pylori in adolescents[J]. Chinese Journal of Contemporary Pediatrics. 2009, 11(03): 210-212
中图分类号: R725.7   

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