Clinical Significance of Cystic Degeneration on Adrenal Cortex in Newborns
LI Xiao-Yu, CHEN Xiu-Tian, LAI Feng, LING Qi-Bo
Department of Pediatrics, First Affiliated Hospital, Sun Yat-Sen University of Medical Sciences, Guangzhou 510080, China
Abstract Objective To study the clinical signif icance of cystic degeneration in the adrenal cortex of newborns. Methods We reviewed the clinical data and morphologic changes of the adrenal c ortex of 70 newborns who died between January 1990 and December 1996. Re sults Cystic degeneration of the adrenal cortex was observed in 29 case s. There was a significantly higher incidence of cystic degeneration in infantswhose gestational age ≤36 w than those whose gestational age>36 w (60% vs 24. 57%, χ2=9.95,P<0.005). We also found a higher incidence of cys tic degeneration in asphyxiated infants than in nonasphyxiated ones. Histochem ical study showed that cystic degeneration was related to lipid depletion in the adrenal cortex. Conclusions Microcyst information in the outer adrenal cortex was associated with prematurity and perinatal hypoxia, which may be a reaction stress situation.
Key words ：
Adrenal gland
Pathology
Cystic degeneration
Newborn
Cite this article:
LI Xiao-Yu,CHEN Xiu-Tian,LAI Feng et al. Clinical Significance of Cystic Degeneration on Adrenal Cortex in Newborns[J]. 中国当代儿科杂志, 2000, 2(5): 317-319.
LI Xiao-Yu,CHEN Xiu-Tian,LAI Feng et al. Clinical Significance of Cystic Degeneration on Adrenal Cortex in Newborns[J]. CJCP, 2000, 2(5): 317-319.
URL:
http://www.zgddek.com/EN/ OR http://www.zgddek.com/EN/Y2000/V2/I5/317
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