Efficacy of bronchoalveolar lavage combined with prone positioning in children with Mycoplasma pneumoniae pneumonia and atelectasis: a prospective randomized controlled study
SA Ri-Na, WANG Ai-Qiong, GAO You-Han, LI Xiao-An, Hugejiletu
Department of Rehabilitation, Ordos Central Hospital, Ordos, Inner Mongolia 017000, China (Hugejiletu, Email: 1206204758@qq.com)
Abstract Objective To study the efficacy of bronchoalveolar lavage (BAL) combined with prone positioning in children with Mycoplasma pneumoniae pneumonia (MPP) and atelectasis and its effect on pulmonary function. Methods A prospective study was conducted on 94 children with MPP and atelectasis who were hospitalized in Ordos Central Hospital of Inner Mongolia from November 2020 to May 2023. The children were randomly divided into a treatment group and a control group, with 47 children in each group. The children in the treatment group were given conventional treatment, BAL, and prone positioning, and those in the control group were given conventional treatment and BAL. The two groups were compared in terms of fever, pulmonary signs, length of hospital stay, lung recruitment, and improvement in pulmonary function. Results Compared with the control group, the treatment group had significantly shorter time to improvement in pulmonary signs and length of hospital stay and a significantly higher rate of lung recruitment on day 7 of hospitalization, on the day of discharge, and at 1 week after discharge (P<0.05). Compared with the control group, the treatment group had significantly higher levels of forced vital capacity (FVC) as a percentage of the predicted value, forced expiratory volume (FEV) in 1 second as a percentage of the predicted value, ratio of FEV in 1 second to FVC, forced expiratory flow at 50% of FVC as a percentage of the predicted value, forced expiratory flow at 75% of FVC as a percentage of the predicted value, and maximal mid-expiratory flow as a percentage of the predicted value on the day of discharge and at 1 week after discharge (P<0.05). There was no significant difference in the time for body temperature to return to normal between the two groups (P>0.05). Conclusions In the treatment of children with MPP and atelectasis, BAL combined with prone positioning can help to shorten the time to improvement in pulmonary signs and the length of hospital stay and promote lung recruitment and improvement in pulmonary function.
SA Ri-Na,WANG Ai-Qiong,GAO You-Han et al. Efficacy of bronchoalveolar lavage combined with prone positioning in children with Mycoplasma pneumoniae pneumonia and atelectasis: a prospective randomized controlled study[J]. CJCP, 2024, 26(1): 31-36.
SA Ri-Na,WANG Ai-Qiong,GAO You-Han et al. Efficacy of bronchoalveolar lavage combined with prone positioning in children with Mycoplasma pneumoniae pneumonia and atelectasis: a prospective randomized controlled study[J]. CJCP, 2024, 26(1): 31-36.
Branch of Pediatric Critical Care Physicians, Chinese Medical Association; Neonatologists Branch of Chinese Medical Association; Gansu Provincial Maternal and Child Health Hospital/Gansu Provincial Central Hospital/Gansu Pediatric Clinical Medical Research Center; Center for Evidence-Based Medicine, School of Basic Medicine, Lanzhou University/WHO Guidelines for Practice and Knowledge Transformation Cooperation Center/Gansu Province Medical Guideline Technology Center. Clinical practice guidelines for bronchoalveolar lavage in Chinese children (2024)[J]. CJCP, 2024, 26(1): 1-13.
