该文报道1例罕见的儿童变应性支气管肺曲霉病合并蛲虫感染病例，探讨其免疫交互机制及个体化治疗策略。10岁7个月女性患儿，以反复咳嗽、喘息为主要表现，实验室检查显示嗜酸性粒细胞显著增多（1.23×10⁹/L），免疫球蛋白（immunoglobulin, Ig）E升高（1 196 IU/mL），烟曲霉IgG抗体（88.61 AU/mL）及烟曲霉m3过敏原特异性IgE抗体（0.37 IU/mL）升高，粪便寄生虫检测确诊蛲虫感染。肺部计算机断层扫描表现为非典型节段性肺实变。通过多学科协作，采用阶梯式抗感染（头孢哌酮舒巴坦→亚胺培南→伏立康唑）、脉冲式驱虫（阿苯达唑）及免疫调节治疗，随访30个月患儿症状完全缓解。该病例揭示了寄生虫-真菌共感染背景下辅助性T细胞2型免疫极化的动态平衡机制，首次提出“寄生虫-真菌-免疫记忆三角”模型，为复杂感染患儿的个体化管理提供新思路。

This article reports a rare pediatric case of allergic bronchopulmonary aspergillosis (ABPA) complicated by concurrent pinworm infection, highlighting immune interaction and individualized, stepwise management. A 10-year-7-month-old girl presented with recurrent cough and wheezing; laboratory testing showed marked eosinophilia (1.23×10⁹/L) and elevated total immunoglobulin E (1 196 IU/mL). Aspergillus fumigatus IgG was 88.61 AU/mL, and Aspergillus fumigatus allergen m3-specific IgE was 0.37 IU/mL. Stool parasite examination confirmed pinworm infection. Chest computed tomography demonstrated atypical segmental pulmonary consolidation. Through multidisciplinary collaboration, stepwise anti-infective therapy (cefoperazone-sulbactam followed by imipenem and then voriconazole), pulsed anthelminthic therapy (albendazole), and immunomodulatory treatment were implemented, resulting in complete symptom resolution and sustained remission over 30 months of follow-up. This case illustrates a dynamic balance of Th2 immune polarization under parasitic-fungal co-infection and, for the first time, proposes a "parasite-fungus-immune memory triangle" conceptual model, offering insights for individualized management in complex pediatric infections.