试管早产儿早期并发症及治疗转归

张静,徐巍,严超英

中国当代儿科杂志 ›› 2013, Vol. 15 ›› Issue (7) : 569-571.

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中国当代儿科杂志 ›› 2013, Vol. 15 ›› Issue (7) : 569-571. DOI: 10.7499/j.issn.1008-8830.2013.07.015
论著·临床研究

试管早产儿早期并发症及治疗转归

  • 张静,徐巍,严超英
作者信息 +

Early complications and treatment outcomes in test-tube premature infants

  • ZHANG Jing, XU Wei, YAN Chao-Ying
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文章历史 +

摘要

目的:探讨试管早产儿早期并发症的发生率及治疗转归。方法:回顾性分析并比较122例试管早产儿与183例自然妊娠早产儿(对照组)母亲围产期情况、出生一般情况及早期并发症的发生情况。结果:两组孕母围产期疾病的发生率差异无统计学意义(P>0.05)。试管早产儿新生儿呼吸窘迫综合征(RDS)发生率(25.4%)高于对照组(12.0%),差异有统计学意义(P<0.05);试管组先天性畸形发生率(3.3%)高于对照组(0%),差异有统计学意义(P<0.05);试管组病死率(9.0%)高于对照组(2.2%),差异有统计学意义(P<0.05)。结论:试管早产儿与自然妊娠早产儿相比,更易患RDS,且畸形率及病死率均较自然受孕儿高,故仍应慎重选择辅助生殖技术的方式,并加强孕产期监护。

Abstract

OBJECTIVE: To study the incidence of early complications and treatment outcomes in premature infants conceived via test tube. METHODS: A retrospective analysis and comparison was conducted on the clinical data of 122 test-tube premature infants and 183 naturally conceived premature infants (control group), including maternal complications, birth conditions and early complications. RESULTS: There was no statistically significant difference in maternal complications between the two groups (P>0.05). The incidence of respiratory distress syndrome (25.4% vs 12.0%; P<0.05) and malformations (3.3% vs 0%; P<0.05) in the test-tube group was statistically higher than in the control group. The mortality rate in the test-tube group was statistically higher than in the control group (9.0% vs 2.2%; P<0.05). CONCLUSIONS: Test-tube premature infants are more likely to suffer from respiratory distress syndrome and have higher incidences of congenital malformations and mortality. Asisted reproductive technique should therefore be chosen cautiously, and enhanced assessment and monitoring is needed during pregnancy.

关键词

并发症 / 治疗转归 / 试管婴儿 / 早产儿

Key words

Complication / Treatment outcome / Test-tube infant / Premature infant

引用本文

导出引用
张静,徐巍,严超英. 试管早产儿早期并发症及治疗转归[J]. 中国当代儿科杂志. 2013, 15(7): 569-571 https://doi.org/10.7499/j.issn.1008-8830.2013.07.015
ZHANG Jing, XU Wei, YAN Chao-Ying. Early complications and treatment outcomes in test-tube premature infants[J]. Chinese Journal of Contemporary Pediatrics. 2013, 15(7): 569-571 https://doi.org/10.7499/j.issn.1008-8830.2013.07.015

参考文献

[1]王建湘,王庆红.试管双胎婴儿临床分析[J].中国当代儿科杂志,2003,5(6):553-554.

[2]Sunderam S, Kissin DM, Flowers L, Anderson JE, Folger SG, Jamieson DJ, et al.Assisted reproductive technology surveillance—United States, 2009[J]. MMWR Surveil Summ, 2012, 61(7): 1-23.

[3]赵平.由诺贝尔生理学奖谈试管婴儿技术[J].生物学通报,2012,46(1):61-62.

[4]王飞凤,王荣,费小阳,何健英.体外受精胚胎移植治疗后分娩的新生儿结局分析[J].浙江医学,2011,33(12):1781-1782.

[5]黄国宁,叶虹,刘红,周丽.体外授精与胚胎移植妊娠成功39例[J].实用妇产科杂志,1998,14(5):260.

[6]Dhont M, De-Sutter P, Ruyssinck G, Van der Elst J, De Neubourg F. Perinatal outcome of pregnancies after assisted  reproduction: a case-control study[J]. Am J Obstet Gynecol, 1999, 181(10): 688-695.

[7]黄越芳,庄思齐,李晓瑜,陈玮琪,陈东平,李易娟.肺表面活性物质治疗早产试管婴儿呼吸窘迫综合症的疗效[J].广东医学,2006,27(8):1250-1252.

[8]张勇,吴忆来,杨育生,王国民,乌丹旦.试管婴儿双胞胎同时发生不完全性腭裂[J].中国口腔颌面外科杂志,2006,4(2):59-160.

[9]Bellieni CV, Bagnoli F, Tei M, De Filippo M, Perrone S, Buonocore G. Increased risk of brain injury in IVF babies[J].Minerva Pediatr, 2011, 63(6): 445-448.

[10]何玲,刘风华.辅助生殖技术与出生缺陷及认知发育[J].中华围产医学杂志,2010,13(2):164-166.


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