母亲抑郁情绪与青少年抑郁症状的关系及家庭干预研究进展

钟莹彦; 从恩朝; 陈剑华

doi:10.7499/j.issn.1008-8830.2504206

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中国当代儿科杂志 ›› 2025, Vol. 27 ›› Issue (10) : 1185-1190. DOI: 10.7499/j.issn.1008-8830.2504206

儿童青少年心理健康专栏

母亲抑郁情绪与青少年抑郁症状的关系及家庭干预研究进展

钟莹彦 ¹ (综述) ,
从恩朝 ¹^,² ,
陈剑华 ¹ (审校)

作者信息 +

Research progress on the relationship between maternal depression and adolescent depressive symptoms and family-based interventions

Author information +

文章历史 +

摘要

青少年抑郁症状发生率不断增加，母亲抑郁情绪是重要的预测因子，该文对其影响机制及干预研究进行综述。母亲抑郁情绪的代际传递效应较父亲更显著。在生物学层面，遗传易感性与神经发育异常构成代际传递的基础；在社会学层面，消极教养方式与家庭环境压力形成恶性循环；在心理学层面，情绪调节缺陷与不安全依恋会放大抑郁的易感性。家庭干预（如认知行为疗法与家庭系统疗法）可缓解代际传递，但需加强纵向研究，未来可融合网络技术开发结构化干预方案。

Abstract

The prevalence of adolescent depressive symptoms has been rising, and maternal depression is a key predictor. This review synthesizes evidence on mechanisms of influence and on intervention research. The intergenerational transmission of risk from maternal depression appears more pronounced than that associated with paternal depression. At the biological level, genetic susceptibility and neurodevelopmental alterations underpin intergenerational transmission; at the social level, negative parenting practices and stressful family environments create a vicious cycle; at the psychological level, deficits in emotion regulation and insecure attachment amplify vulnerability to depression. Family-based interventions, including cognitive-behavioral therapy and family systems therapy, can mitigate intergenerational transmission. However, more longitudinal research is needed, and future work may integrate digital technologies to develop structured intervention protocols.

导出引用

钟莹彦, 从恩朝, 陈剑华. 母亲抑郁情绪与青少年抑郁症状的关系及家庭干预研究进展[J]. 中国当代儿科杂志. 2025, 27(10): 1185-1190 https://doi.org/10.7499/j.issn.1008-8830.2504206

Ying-Yan ZHONG, En-Zhao CONG, Jian-Hua CHEN. Research progress on the relationship between maternal depression and adolescent depressive symptoms and family-based interventions[J]. Chinese Journal of Contemporary Pediatrics. 2025, 27(10): 1185-1190 https://doi.org/10.7499/j.issn.1008-8830.2504206

参考文献

列表( 原文顺序 | 文献年度倒序 | 文中引用次数倒序 ) 可视化分析

[1]

Askari

, Olfson

, Belsky

, et al. The influence of the great recession on adolescent major depressive episodes and treatment in the United States: an interrupted time series analysis[J]. J Adolesc Health, 2024, 74(1): 51-59. DOI: 10.1016/j.jadohealth.2023.08.023 .

https://www.ncbi.nlm.nih.gov/pubmed/37831049

本文引用 [1]

[2]	Daly M. Prevalence of depression among adolescents in the U.S. from 2009 to 2019: analysis of trends by sex, race/ethnicity, and income[J]. J Adolesc Health, 2022, 70(3): 496-499. DOI: 10.1016/j.jadohealth.2021.08.026 . https://www.ncbi.nlm.nih.gov/pubmed/34663534

[3]	Shorey S, Ng ED, Wong CHJ. Global prevalence of depression and elevated depressive symptoms among adolescents: a systematic review and meta-analysis[J]. Br J Clin Psychol, 2022, 61(2): 287-305. DOI: 10.1111/bjc.12333 . https://www.ncbi.nlm.nih.gov/pubmed/34569066 本文引用 [1]

[4]

Yue

, Hong

, Guo

, et al. Gender differences in the association between cigarette smoking, alcohol consumption and depressive symptoms: a cross-sectional study among Chinese adolescents[J]. Sci Rep, 2015, 5: 17959. PMCID: PMC4671152. DOI: 10.1038/srep17959 .

https://www.ncbi.nlm.nih.gov/pubmed/26639938

本文引用 [1]

[5]	陈祉妍, 傅小兰, 张侃, 等. 中国国民心理健康发展报告（2019—2020）[M]. 北京: 社会科学文献出版社, 2021.

[6]

Zhou

, Zhang

, Wang

, et al. Prevalence and socio-demographic correlates of psychological health problems in Chinese adolescents during the outbreak of COVID-19[J]. Eur Child Adolesc Psychiatry, 2020, 29(6): 749-758. PMCID: PMC7196181. DOI: 10.1007/s00787-020-01541-4 .

https://www.ncbi.nlm.nih.gov/pubmed/32363492

本文引用 [1]

[7]	Thapar A, Eyre O, Patel V, et al. Depression in young people[J]. Lancet, 2022, 400(10352): 617-631. DOI: 10.1016/S0140-6736(22)01012-1 . https://www.ncbi.nlm.nih.gov/pubmed/35940184 本文引用 [1]

[8]	Lu B, Lin L, Su X. Global burden of depression or depressive symptoms in children and adolescents: a systematic review and meta-analysis[J]. J Affect Disord, 2024, 354: 553-562. DOI: 10.1016/j.jad.2024.03.074 . https://www.ncbi.nlm.nih.gov/pubmed/38490591 本文引用 [1]

[9]	肖玉, 肖依, 李凌. 新型冠状病毒感染疫情期间母亲抑郁焦虑与青少年抑郁的关系及影响因素[J]. 中国健康心理学杂志, 2023, 31(6): 908-913. DOI: 10.13342/j.cnki.cjhp.2023.06.022 . 本文引用 [1]

[10]

Walker

, Peters

, de Rooij

, et al. The long-term impact of maternal anxiety and depression postpartum and in early childhood on child and paternal mental health at 11-12 years follow-up[J]. Front Psychiatry, 2020, 11: 562237. PMCID: PMC7531027. DOI: 10.3389/fpsyt.2020.562237 .

https://www.ncbi.nlm.nih.gov/pubmed/33192681

本文引用 [1]

[11]	李跃, 钟莹彦, 从恩朝, 等. 父母婚姻适应与青少年抑郁症状的关系: 母亲抑郁症状的中介作用[J]. 神经疾病与精神卫生, 2023, 23(10): 691-696. DOI: 10.3969/j.issn.1009-6574.2023.10.002 . 本文引用 [1]

[12]

Donado

, Friedrich

, Kossowsky

, et al. Exposure to parental depressive symptoms: a longitudinal analysis on the association with adolescents' depressive symptoms and adjustment problems[J]. J Dev Behav Pediatr, 2020, 41(7): 522-533. DOI: 10.1097/DBP.0000000000000820 .

https://www.ncbi.nlm.nih.gov/pubmed/32576787

本文引用 [1]

[13]	李雨婷, 钟莹彦, 陈剑华, 等. 母亲职业倦怠和青少年抑郁的关系: 母亲抑郁和教养方式的链式中介作用[J]. 中国当代儿科杂志, 2023, 25(2): 186-192. PMCID: PMC9979380. DOI: 10.7499/j.issn.1008-8830.2208026 . https://www.ncbi.nlm.nih.gov/pubmed/36854696 本文引用 [2]

[14]	杨逸群, 陈亮, 纪林芹, 等. 母亲抑郁对青少年抑郁的影响: 亲子关系的中介作用与青少年消极情绪性的调节作用[J]. 心理发展与教育, 2017, 33(3): 368-377. DOI: 10.16187/j.cnki.issn1001-4918.2017.03.15 . 本文引用 [2]

[15]	廖友国, 连榕, 张妍, 等. 青少年与父母抑郁情绪的关系: 交叉滞后分析[J]. 心理科学, 2022, 45(4): 973-979. DOI: 10.16719/j.cnki.1671-6981.20220427 . 本文引用 [2]

[16]

Dunning

, McArthur

, Abramson

, et al. Linking maternal depression to adolescent internalizing symptoms: transmission of cognitive vulnerabilities[J]. J Youth Adolesc, 2021, 50(2): 324-335. PMCID: PMC7878334. DOI: 10.1007/s10964-020-01342-7 .

https://www.ncbi.nlm.nih.gov/pubmed/33165756

本文引用 [1]

[17]	Goodman SH, Gotlib IH. Risk for psychopathology in the children of depressed mothers: a developmental model for understanding mechanisms of transmission[J]. Psychol Rev, 1999, 106(3): 458-490. DOI: 10.1037/0033-295x.106.3.458 . https://www.ncbi.nlm.nih.gov/pubmed/10467895 本文引用 [1]

[18]	Connelly JP, O'Connell M. Gender differences in vulnerability to maternal depression during early adolescence: girls appear more susceptible than boys[J]. Psychol Sch, 2022, 59(2): 297-315. DOI: 10.1002/pits.22609 . 本文引用 [1]

[19]	Hastings PD, Ugarte E, Mashash M, et al. The codevelopment of adolescents' and parents' anxiety and depression: moderating influences of youth gender and psychophysiology[J]. Depress Anxiety, 2021, 38(12): 1234-1244. DOI: 10.1002/da.23183 . https://www.ncbi.nlm.nih.gov/pubmed/34110070 本文引用 [1]

[20]	刘明杰, 郭菲, 陈祉妍. 父亲共同养育对子女抑郁的影响: 青少年正念特质的中介作用和母亲正念教养的调节[J]. 中国临床心理学杂志, 2022, 30(2): 372-376. DOI: 10.16128/j.cnki.1005-3611.2022.02.025 . 本文引用 [1]

[21]	陈楚芳, 郭菲, 陈祉妍. 父亲共同养育对青少年抑郁的影响: 母亲心理控制和青少年坚毅的多重中介作用[J]. 中国临床心理学杂志, 2021, 29(4): 734-738. DOI: 10.16128/j.cnki.1005-3611.2021.04.014 . 本文引用 [1]

[22]

Wang

, Tian

, Zhang

. Interactions between the combined genotypes of 5-HTTLPR and BDNF Val66Met polymorphisms and parenting on adolescent depressive symptoms: a three-year longitudinal study[J]. J Affect Disord, 2020, 265: 104-111. DOI: 10.1016/j.jad.2020.01.064 .

https://www.ncbi.nlm.nih.gov/pubmed/32090731

本文引用 [1]

[23]

Zhang

, Yue

, Li

. The association of FKBP5 gene polymorphism with genetic susceptibility to depression and response to antidepressant treatment: a systematic review[J]. BMC Psychiatry, 2024, 24(1): 274. PMCID: PMC11010372. DOI: 10.1186/s12888-024-05717-z .

https://www.ncbi.nlm.nih.gov/pubmed/38609904

本文引用 [1]

[24]	曹衍淼, 张文新. 多巴胺系统基因与母亲教养行为对青少年抑郁的影响: 一项多基因研究[J]. 心理学报, 2019, 51(10): 1102-1115. DOI: 10.3724/SP.J.1041.2019.01102 . 本文引用 [1]

[25]	Alex AM, Buss C, Davis EP, et al. Genetic influences on the developing young brain and risk for neuropsychiatric disorders[J]. Biol Psychiatry, 2023, 93(10): 905-920. PMCID: PMC10136952. DOI: 10.1016/j.biopsych.2023.01.013 . https://www.ncbi.nlm.nih.gov/pubmed/36932005 本文引用 [1]

[26]	Starr LR, Huang M. HPA-axis multilocus genetic variation moderates associations between environmental stress and depressive symptoms among adolescents[J]. Dev Psychopathol, 2019, 31(4): 1339-1352. DOI: 10.1017/S0954579418000779 . https://www.ncbi.nlm.nih.gov/pubmed/30394263 本文引用 [1]

[27]	Ulmer-Yaniv A, Djalovski A, Priel A, et al. Maternal depression alters stress and immune biomarkers in mother and child[J]. Depress Anxiety, 2018, 35(12): 1145-1157. DOI: 10.1002/da.22818 . https://www.ncbi.nlm.nih.gov/pubmed/30133052 本文引用 [1]

[28]

van der Knaap

NJF

, Klumpers

, El Marroun

, et al. Maternal depressive symptoms during pregnancy are associated with amygdala hyperresponsivity in children[J]. Eur Child Adolesc Psychiatry, 2018, 27(1): 57-64. PMCID: PMC5799325. DOI: 10.1007/s00787-017-1015-x .

https://www.ncbi.nlm.nih.gov/pubmed/28667426

本文引用 [1]

[29]	Aljabali AAA, Alkaraki AK, Gammoh O, et al. Deciphering depression: epigenetic mechanisms and treatment strategies[J]. Biology (Basel), 2024, 13(8): 638. PMCID: PMC11351889. DOI: 10.3390/biology13080638 . https://www.ncbi.nlm.nih.gov/pubmed/39194576 本文引用 [1]

[30]	Bolsoni-Silva AT, Pizeta FA, Loureiro SR. Parenting practices, maternal depression and behavior problems: associations, prediction and moderation[J]. Paidéia, 2023, 33: e3334. DOI: 10.1590/1982-4327e3334 . 本文引用 [1]

[31]	张俊先, 陈杰, 李新影. 母亲抑郁与青少年认知重评的关系: 教养方式的中介作用[J]. 中国临床心理学杂志, 2011, 19(5): 690-691. DOI: 10.16128/j.cnki.1005-3611.2011.05.030 . 本文引用 [1]

[32]

Olino

, Finsaas

, Dyson

, et al. A multimethod, multiinformant study of early childhood temperament and depression and anxiety symptoms in adolescence[J]. J Psychopathol Clin Sci, 2022, 131(7): 741-753. PMCID: PMC9560959. DOI: 10.1037/abn0000769 .

https://www.ncbi.nlm.nih.gov/pubmed/35708930

本文引用 [1]

[33]

Lee

, Cederbaum

, Davis

, et al. Maternal and adolescent depressive symptoms and family conflict: an autoregressive cross-lagged examination of competing models in multi-stressed mothers and adolescents[J]. Fam Process, 2023, 62(1): 254-271. DOI: 10.1111/famp.12779 .

https://www.ncbi.nlm.nih.gov/pubmed/35545438

本文引用 [1]

[34]

Jin

, Liu

, Li

, et al. Longitudinal associations between family conflict, intergenerational transmission, and adolescents' depressive symptoms: evidence from China Family Panel studies (2016-2020)[J]. Child Adolesc Psychiatry Ment Health, 2025, 19(1): 10. PMCID: PMC11834216. DOI: 10.1186/s13034-025-00866-9 .

https://www.ncbi.nlm.nih.gov/pubmed/39962501

本文引用 [1]

[35]	Pinquart M. Associations of parenting dimensions and styles with internalizing symptoms in children and adolescents: a meta-analysis[J]. Marriage Fam Rev, 2016, 53(7): 613-640. DOI: 10.1080/01494929.2016.1247761 . 本文引用 [1]

[36]	Choi JY, Eoh Y, Kang JH. Emotion socialization mediates the short-term longitudinal relationship between mothers' depressive symptoms and children's emotion regulation[J]. Curr Psychol, 2024, 43(4): 3599-3606. DOI: 10.1007/s12144-023-04528-x . 本文引用 [1]

[37]	Gross JJ. Emotion regulation: current status and future prospects[J]. Psychol Inq, 2015, 26(1): 1-26. DOI: 10.1080/1047840X.2014.940781 . 本文引用 [1]

[38]	Modi HH, Davis MM, Miernicki ME, et al. Maternal antecedents to adolescent girls' neural regulation of emotion[J]. J Res Adolesc, 2020, 30(3): 581-598. DOI: 10.1111/jora.12545 . https://www.ncbi.nlm.nih.gov/pubmed/32030842 本文引用 [1]

[39]	Phillips JJ, Smith CL, Bell MA. Associations between maternal personality dysfunction and emotion suppression and adolescent emotion suppression[J]. Borderline Personal Disord Emot Dysregul, 2024, 11(1): 30. PMID: 39593125 PMCID:PMC11600757. DOI: 10.1186/s40479-024-00273-0 . 本文引用 [1]

[40]	Felton JW, Schwartz KTG, Oddo LE, et al. Transactional patterns of depressive symptoms between mothers and adolescents: the role of emotion regulation[J]. Depress Anxiety, 2021, 38(12): 1225-1233. PMCID: PMC8665117. DOI: 10.1002/da.23225 . https://www.ncbi.nlm.nih.gov/pubmed/34762765 本文引用 [1]

[41]

Gadassi-Polack

, Chertkof

, Kober

, et al. Maternal depression history moderates the association between criticism (but not praise) and depressive symptoms in youth[J]. Res Child Adolesc Psychopathol, 2021, 49(8): 1097-1110. PMCID: PMC8295739. DOI: 10.1007/s10802-021-00803-2 .

https://www.ncbi.nlm.nih.gov/pubmed/33725232

本文引用 [1]

[42]	Śliwerski A, Kossakowska K, Jarecka K, et al. The effect of maternal depression on infant attachment: a systematic review[J]. Int J Environ Res Public Health, 2020, 17(8): 2675. PMCID: PMC7216154. DOI: 10.3390/ijerph17082675 . https://www.ncbi.nlm.nih.gov/pubmed/32295106 本文引用 [1]

[43]	Murray L, Halligan SL, Adams G, et al. Socioemotional development in adolescents at risk for depression: the role of maternal depression and attachment style[J]. Dev Psychopathol, 2006, 18(2): 489-516. DOI: 10.1017/S0954579406060263 . https://www.ncbi.nlm.nih.gov/pubmed/16600065 本文引用 [1]

[44]	Griffith JM, Young JF, Hankin BL. Longitudinal coupling of depression in parent-adolescent dyads: within- and between-dyad effects over time[J]. Clin Psychol Sci, 2021, 9(6): 1059-1079. PMCID: PMC8740952. DOI: 10.1177/2167702621998313 . https://www.ncbi.nlm.nih.gov/pubmed/35003905 本文引用 [1]

[45]	苗懿, 李隽逸, 黄佩姗, 等. 不同因素对青少年抑郁障碍非自杀性自伤行为的影响[J]. 中山大学学报（医学科学版）, 2025, 46(1): 123-131. DOI: 10.13471/j.cnki.j.sun.yat-sen.univ(med.sci).2025.0114 . 本文引用 [1]

[46]	Hughes JL, Asarnow JR. Family intervention strategies for adolescent depression[J]. Pediatr Ann, 2011, 40(6): 314-318. DOI: 10.3928/00904481-20110512-07 . https://www.ncbi.nlm.nih.gov/pubmed/21678890 本文引用 [1]

[47]

Shpigel

, Diamond

. Changes in parenting behaviors, attachment, depressive symptoms, and suicidal ideation in attachment-based family therapy for depressive and suicidal adolescents[J]. J Marital Fam Ther, 2012, 38 : 271-283. DOI: 10.1111/j.1752-0606.2012.00295.x .

https://www.ncbi.nlm.nih.gov/pubmed/22765339

本文引用 [1] 摘要

Suppl 1

[48]	Smith JA, Bandealy A, Browne DT. A case study of virtually delivered emotion-focused family therapy[J]. J Marital Fam Ther, 2023, 49(3): 692-713. DOI: 10.1111/jmft.12648 . https://www.ncbi.nlm.nih.gov/pubmed/37365937 本文引用 [1]