目的：探讨非营养性吸吮在需要机械通气辅助治疗的早产儿中的作用。方法：将68例需要机械通气辅助治疗的早产儿随机分为观察组（n=35）和对照组（n=33）。观察组进行非营养性吸吮，对照组不进行非营养性吸吮。比较两组患儿达全胃肠道喂养时间、恢复至出生体重时间、体重增长速度、住院时间、喂养耐受性、机械通气并发症等。结果：与对照组比较，观察组达全胃肠道营养时间及住院时间缩短（P0.05）。结论：在需要机械通气治疗的早产儿中采用非营养性吸吮可加快其生长发育速度、缩短住院时间，并能提高喂养耐受性，而机械通气并发症发生率没有上升。

OBJECTIVE: To study the role of non-nutritive sucking in preterm infants requiring mechanical ventilation therapy. METHODS: In a study of 68 preterm infants requiring mechanical ventilation, a randomly selected observation group of 35 infants was provided with non-nutritive sucking and a control group of 33 infants was not. The time to reach full enteral feeding, birth weight recovery time, body weight growth rate, hospitalization time, feeding tolerance and mechanical ventilation-related complications were compared between the two groups. RESULTS: The time to reach full enteral feeding and hospitalization time were shorter (P<0.01), the incidence of feeding intolerance was lower (P<0.05), and the body weight growth rate was higher (P<0.05) in the observation group than in the control group. There were no significant differences in the birth weight recovery time and the incidence of mechanical ventilation-related complications between the two groups. CONCLUSIONS: The use of non-nutritive sucking can increase growth rate, shorten hospitalization time and improve feeding tolerance in preterm infants requiring mechanical ventilation therapy. Moreover, it does not result in an increase in mechanical ventilation-related complications.