Abstract:Objective To study the clinical application of ultrasonic cardiac output monitor (USCOM) in evaluation of cardiac function in children with severe pneumonia. Methods Twenty-nine children with severe pneumonia were enrolled in the observation group and forty-three children with common pneumonia were enrolled in the control group. The USCOM was used to measure the cardiac function indices in the two groups. The results were compared between the two groups. The changes in cardiac function indices after treatment were evaluated in the observation group. Results The observation group had a significantly higher heart rate and significantly lower cardiac output, systolic volume, and aortic peak velocity than the control group (P < 0.05). There were no significant differences in cardiac index or systemic vascular resistance between the two groups (P > 0.05). In the observation group, the heart rate, cardiac output, systolic volume, aortic peak velocity, cardiac index, and systemic vascular resistance were significantly improved after treatment (P < 0.05). Conclusions The USCOM is a fast, convenient, and accurate approach for dynamic measurement of cardiac function and overall circulation state in children with severe pneumonia. The USCOM can provide a basis for diagnosis, treatment, and evaluation of the disease, which is quite useful in clinical practice.
FAN Juan,CHEN Zhi-Ying,CHEN Peng-Yuan et al. Application of ultrasonic cardiac output monitor in evaluation of cardiac function in children with severe pneumonia[J]. CJCP, 2016, 18(9): 817-820.
Rudan I, O'Brien KL, Nair H, et al. Epidemiology and etiology of childhood pneumonia in 2010:estimates of incidence, severe morbidity, mortality, underlying risk factors and causative pathogens for 192 countries[J]. J Glob Health, 2013, 3(1):010401.
[2]
Scott JA, Brooks WA, Peiris JS, et al. Pneumonia research to reduce childhood mortality in the developing world[J]. J Clin Invest, 2008, 118(4):1291-1300.
Dhanani S, Barrowman NJ, Ward RE, et al. Intra-and interobserver reliability using a noninvasive ultrasound cardiac output monitor in healthy anesthetized children[J]. Paediatr Anaesth, 2011, 21(8):858-864.
[6]
Beltramo F, Menteer J, Razavi A, et al. Validation of an Ultrasound Cardiac Output Monitor as a Bedside Tool for Pediatric Patients[J]. Pediatr Cardiol, 2016, 37(1):177-183.
He SR, Zhang C, Liu YM, et al. Accuracy of the ultrasonic cardiac output monitor in healthy term neonates during postnatal circulatory adaptation[J]. Chin Med J (Engl), 2011, 124(15):2284-2289.
[10]
Kanmaz HG, Sarikabadayi YU, Canpolat E, et al. Effects of red cell transfusion on cardiac output and perfusion index in preterm infants[J]. Early Hum Dev, 2013, 89(9):683-686.
[11]
He SR, Sun X, Zhang C, et al. Measurement of systemic oxygen delivery and inotropy in healthy term neonates with the Ultrasonic Cardiac Output Monitor (USCOM)[J]. Early Hum Dev, 2013, 89(5):289-294.
[12]
Feldman C, Anderson R. Community-acquired pneumonia:pathogenesis of acute cardiac events and potential adjunctive therapies[J]. Chest, 2015, 148(2):523-532.
[13]
Hu D, Liu Y, Tao H, et al. Clinical value of plasma B-type natriuretic peptide assay in pediatric pneumonia accompanied by heart failure[J]. Exp Ther Med, 2015, 10(6):2175-2179.
[14]
Gregory SD, Cooney H, Diab S, et al. In vitro evaluation of an ultrasonic cardiac output monitoring (USCOM) device[J]. J Clin Monit Comput, 2016, 30(1):69-75.
[15]
Zorko DJ, Choong K, Gilleland J, et al. Urgent ultrasound guided hemodynamic assessments by a pediatric medical emergency team:a pilot study[J]. PLoS One, 2013, 8(6):e66951.
[16]
Chong SW, Peyton PJ. A meta-analysis of the accuracy and precision of the ultrasonic cardiac output monitor (USCOM)[J]. Anaesthesia, 2012, 67(11):1266-1271.
[17]
Chand R, Mehta Y, Trehan N. Cardiac output estimation with a new Doppler device after off-pump coronary artery bypass surgery[J]. J Cardiothorac Vasc Anesth, 2006, 20(3):315-319.
[18]
Wongsirimetheekul T, Khositseth A, Lertbunrian R. Noninvasive cardiac output assessment in critically ill paediatric patients[J]. Acta Cardiol, 2014, 69(2):167-173.
[19]
Minneci PC, Kilbaugh TJ, Chandler HK, et al. Factors associated with mortality in pediatric patients requiring extracorporeal life support for severe pneumonia[J]. Pediatr Crit Care Med, 2013, 14(1):e26-e33.
Chang AC. Determination of cardiac output in critically ill children:are we any closer to the ideal methodology?[J]. Pediatr Crit Care Med, 2012, 13(1):99.