早产儿代谢性骨病临床管理专家共识（2021年）

doi:10.7499/j.issn.1008-8830.2105152

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摘要早产儿代谢性骨病（metabolic bone disease of prematurity，MBDP）是由于机体钙磷代谢紊乱导致骨矿物质含量减少的全身性骨骼疾病。我国目前对MBDP尚缺乏深入研究和系统认识，在临床管理方面存在很多不规范之处。现基于国内外相关研究，采用证据推荐分级的评估、制定与评价方法（Grading of Recommendations Assessment，Development and Evaluation），制定MBDP临床管理专家共识，从MBDP的高危因素、筛查/诊断、预防、治疗及出院后随访等5个方面提出推荐意见，旨在为相关从业人员提供 MBDP临床管理的建议，以减少MBDP的发生及改善其近远期预后。

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	常艳美
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	陈平洋
	封志纯

关键词 ：代谢性骨病, 专家共识, 骨质减少, 骨矿化和生长, 早产儿

Abstract：Metabolic bone disease of prematurity (MBDP) is a systemic bone disease with a reduction in bone mineral content due to disorder of calcium and phosphorus metabolism. There is still a lack of in-depth research and systematic understanding of MBDP in China, and there are many irregularities in clinical management of this disease. Based on relevant studies in China and overseas, Grading of Recommendations Assessment, Development and Evaluation was used to develop the expert consensus on the clinical management of MBDP, which provides recommendations from the following five aspects: high-risk factors, screening/diagnosis, prevention, treatment, and post-discharge follow-up of MBDP, so as to provide relevant practitioners with recommendations on the clinical management of MBDP to reduce the incidence rate of MBDP and improve its short- and long-term prognosis.

Key words： Metabolic bone disease Expert consensus Osteopenia Bone mineralization and growth Preterm infant

收稿日期: 2021-06-01

通讯作者: 童笑梅，女，教授，Email：tongxm2007@126.com E-mail: tongxm2007@126.com

作者简介: 常艳美，女，博士，副主任医师；林新祝，男，本科，主任医师；张蓉，女，博士，主任医师；刘喜红，女，博士，主任医师；

引用本文:

常艳美,林新祝,张蓉等. 早产儿代谢性骨病临床管理专家共识（2021年）[J]. 中国当代儿科杂志, 2021, 23(8): 761-772.

Yan-Mei CHANG,Xin-Zhu LIN,Rong ZHANG et al. Expert consensus on clinical management of metabolic bone disease of prematurity (2021)[J]. CJCP, 2021, 23(8): 761-772.

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