OBJECTIVE: To study the relationship between α-smooth muscle actin(α-SMA) and clinical symptoms(hypertension and hyperlipoproteinemia ) in children with mesangial proliferative glomerulonephritis(MsPGN). METHODS: Expression of α-SMA was detected using immunohistochemistry and computer image evaluation in 33 children with MsPGN. RESULTS: The expression of α-SMA was higher in MsPGN children with hypertension and/or hyperlipoproteinemia than that in MsPGN children without hypertension and/or hyperlipoproteinemia(P < 0.05). CONCLUSIONS: Expression of α-SMA by mesangial cells appears to be activated by hypertension and hyperlipoproteinemia in children with MsPGN."/>
系膜增殖性肾小球肾炎患儿α-平滑肌肌动蛋白表达与血脂及血压的关系探讨
Abstract：OBJECTIVE: To study the relationship between α-smooth muscle actin(α-SMA) and clinical symptoms(hypertension and hyperlipoproteinemia ) in children with mesangial proliferative glomerulonephritis(MsPGN). METHODS: Expression of α-SMA was detected using immunohistochemistry and computer image evaluation in 33 children with MsPGN. RESULTS: The expression of α-SMA was higher in MsPGN children with hypertension and/or hyperlipoproteinemia than that in MsPGN children without hypertension and/or hyperlipoproteinemia(P < 0.05). CONCLUSIONS: Expression of α-SMA by mesangial cells appears to be activated by hypertension and hyperlipoproteinemia in children with MsPGN.
HU Ling. Relationship between the Expression of α－mooth Muscle Actin and Clinical ymptoms in Children with Mesangial Proliferative Glomerulonephritis[J]. CJCP, 2002, 4(2): 106-108.
