The value of high-frequency ultrasound in the diagnosis of duchenne muscular dystrophy in children
SHI Yan-Rong, LIU Xiao-Qing, DAI Hong, LU Dian-Yuan, NI Jun-Yi, LI Xi-Hua
Department of Pediatrics, Xinhua Hospital (Chongming) Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 202150, China. cmcpho1@163.com
Abstract：OBJECTIVE: To study the value of high-frequency ultrasound in the diagnosis of duchenne muscular dystrophy diseases (DMD) in children. METHODS: Eight children with DMD were enrolled as DMD group and 10 healthy children as the control group. The echogenicity of the rectus femoris muscle and the gap between the gastrocnemius and soleus muscles in the two groups were detected by high-frequency ultrasound. RESULTS: Compared with the control group, rectus femoris and gastrocnemius muscles in the DMD group showed increased echogenicity and their muscle fibers were arranged irregularly, and the gap between the gastrocnemius and soleus muscles became wilder (P<0.01). CONCLUSIONS: High-frequency ultrasound is valuable in the diagnosis of DMD.
SHI Yan-Rong,LIU Xiao-Qing,DAI Hong et al. The value of high-frequency ultrasound in the diagnosis of duchenne muscular dystrophy in children[J]. CJCP, 2012, 14(07): 533-535.
［10］Maurits NM, Beenakker EA, van schaik DE, Fock JM, Van der Hoeven JH. Muscle ultrasound in children: normal values and application to neuromuscular disorders［J］. Ultrasound Med Biol, 2004, 30(8): 1017-1027.
［11］Zaidman CM, Connolly AM, Malkus EC, Florence JM, Pestronk A. Quantitative ultrasound using backscatter analysis in Duchenne and Becker muscular dystrophy［J］. Neuromuscul Disord, 2010, 20(12): 805-809.
［12］Escolar DM, Hache LP, Clemens PR, Cnaan A, McDonald CM, Viswanathan V, et al. Randomized, blinded trial of weekend vs daily prednisone in Duchenne muscular dystrophy［J］. Neurology, 2011, 77(5): 444-452.
