Perinatal high-risk factors for necrotizing enterocolitis in preterm infants：a case-control study
WANG Rui-Juan, KONG Xiang-Yong, CAI Na, CHEN Ying, FENG Zhi-Chun
Neonatal Intensive Care Unit For Very Preterm Infants, Bayi Children's Hospital Affiliated to the Beijing Military Region General Hospital, Beijing 100700, China
Abstract：Objective To study the timing of presentation and perinatal high-risk factors for necrotizing enterocolitis (NEC) in preterm infants with a gestational age of Methods A case-control study was conducted in 49 preterm infants with NEC (gestational age Results The median age of onset was 17.5 days (range: 3-106 d) in preterm infants with NEC. Sex, being small for gestational age, delivery mode and antenatal corticosteroid therapy were not associated with the development of NEC; low gestational age, low birth weight and neonatal asphyxia increased the risk of NEC, and low gestational age was identified as an independent high-risk factor for the development of NEC. Conclusions Low gestational age is an important risk factor for the development NEC in preterm infants under 33 weeks' gestation, and the median age of onset is 17.5 days.
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