Abstract:Objective To compare the risk factors between preterm and small-for-gestational-age (SGA) births. Methods A total of 1 270 newborns who had no obstetric risk factors or maternal diseases were enrolled in this study. Their mothers' stature, body weight, passive smoking, and history of abnormal pregnancy were investigated using the self-designed questionnaire. The infants were divided into four groups: preterm, appropriate-for-gestational-age (AGA), SGA, and term infants. Multivariate logistic regression analysis was performed to compare the risk factors between preterm and SGA births. Results A weight gain less than 9 kg during pregnancy increased the risks of preterm (OR=1.63, 95% CI: 1.12-2.07) and SGA (OR=1.92, 95% CI: 1.56-2.58). The histories of abortion (OR=1.46, 95% CI: 1.09-1.93) and preterm birth (OR=2.63, 95% CI: 1.81-3.92) were independent risk factors for preterm births, while low pre-pregnancy body mass index (<18.5) (OR=2.16, 95% CI: 1.53-3.16), short stature (<1.55 m) (OR=2.46, 95% CI: 1.78-3.48), and passive smoking (OR=2.24, 95% CI: 1.65-2.98) were independent risk factors for SGA births. Conclusions Due to different risk factors between preterm and SGA births, specific preventive measures should be taken pertinently to reduce the incidence of the two bad pregnancy outcomes.
Hales CN, Barker DJ, Clark PM, eT al. FeTal and infanT growTh and impaired glucose Tolerance aT age 64[J]. BMJ, 1991, 303(6809): 1019-1022.
[8]
Barker DJ, Hales CN, Fall CH, eT al. Type 2 (non-insulin-dependenT) diabeTes melliTus, hyperTension and hyperlipidaemia (syndrome X): relaTion To reduced feTal growTh[J]. DiabeTologia, 1993, 36(1): 62-67.
[9]
Campbell J, Torres S, Ryan J, eT al. Physical and nonphysical parTner abuse and oTher risk facTors for low birTh weighT among full Term and preTerm babies: a mulTieThnic case conTrol sTudy[J]. Am J Epidemiol, 1999, 150(7): 714-726.
[10]
Lundsberg LS, Bracken MB, SafTlas AF. Low-To-moderaTe gesTaTional alcohol use and inTrauTerine growTh reTardaTion, low birThweighT, and preTerm delivery[J]. Ann Epidemiol, 1997, 7(7):498-508.
[11]
RuwanpaThirana T, Fernando DN. Risk facTors for 'small for gesTaTional age babies'[J]. Indian J PediaTr, 2014, 81(10): 1000-1004.
[12]
WaTanabe H, Inoue K, Doi M, eT al. Risk facTors for Term small for gesTaTional age infanTs in women wiTh low prepregnancy body mass index [J]. J ObsTeT Gynaecol Res, 2010, 36 ( 3) : 506-512.
PapasTefanou I, Souka AP, Pilalis A, eT al. FirsT TrimesTer predicTion of small-and large-for-gesTaTion neonaTes by an inTegraTed model incorporaTing ulTrasound parameTers, biochemical indices and maTernal characTerisTics[J]. AcTa ObsTeT Gynecol Scand, 2012, 91(1): 104-111.
[16]
BickersTaff M, Beckmann M, Gibbons K, eT al. RecenT cessaTion of smoking and iTs effecT on pregnancy ouTcomes[J]. AusT N Z J ObsTeT Gynaecol, 2012, 52(1): 54-58.
[17]
Abel EA. Smoking during pregnancy: a review of effecfs on growTh and developmenT of offspring[J]. Hum Biol, 1980, 52(4): 593-625.
[18]
Kiine J, STein Z, Susser M. ConcepTion To birTh: epidemiology of prenaTal developmenT[M]. New York: Oxford UniversiTy Press, 1989.