Abstract:Objective To study the clinical characteristics of childhood Henoch-Schonlein purpura (HSP) on the Tibetan Plateau, China. Methods One hundred and twenty-five HSP children admitted to Shannan People's Hospital, Tibet, were assigned to the observation group, and 96 HSP children admitted to Wuhan Children's Hospital were assigned to the control group. The disease characteristics, clinical manifestations, treatment, and prognosis in both groups were retrospectively analyzed and compared. Results The mean age of HSP onset and the female-to-male ratio in the observation group were both significantly higher than in the control group (PPPPP>0.05). Only 2.4% of the patients (3 cases) in the observation group had recurrent attack during follow-up, which was significantly lower than that in the control group (16.7%; PConclusions Childhood HSP on the Tibetan Plateau shows partial differences in disease characteristics, clinical manifestations, and laboratory measurements compared with that in the plain area. The overall prognosis is better and the recurrent rate is lower among HSP children on the Tibetan Plateau.
YANG Zhen,GUO Lin,XIONG Hao et al. Clinical analysis of childhood Henoch-Schonlein purpura on the Tibetan Plateau, China[J]. CJCP, 2014, 16(12): 1231-1235.