Abstract:Objective To investigate the early predictors of necrotizing pneumonia in children. Methods The clinical data of 43 children with necrotizing pneumonia and 83 children with lobar pneumonia were retrospectively analyzed. Sex, age, the number of days with fever, laboratory examination results, and bronchoscopic findings were compared between the two groups. The multiple logistic regression analysis was used to identify the early predictors of necrotizing pneumonia. Results The necrotizing pneumonia group had a higher percentage of girls than the lobar pneumonia group (PPPConclusions Increased WBC (≥15.1×109/L), increased hs-CRP (≥121.5 mg/L), increased serum LDH (≥353.5 U/L), and the presence of sputum bolt under a bronchoscope which needs to be removed with biopsy forceps and rice-water-like bronchoalveolar lavage fluid may be the early predictors of necrotizing pneumonia in children.
Lemaître C, Angoulvant F, Gabor F, et al. Necrotizing pneumonia in children: report of 41 cases between 2006 and 2011 in a French tertiary care center[J]. Pediatr Infect Dis J, 2013, 32(10): 1146-1149.
[5]
Sawicki GS, Lu FL, Valim C, et al. Necrotizing pneumonia is an increasingly detected complication of pneumonia in children[J]. Eur Res Pir J, 2008, 31(6): 1285-1291.
[6]
Krenke K, Sanocki M, Urbankowska E, et al. Necrotizing pneumonia and its complications in children[J]. Adv Exp Med Biol, 2015, 857: 9-17.
[7]
Macedo M, Meyer KF, Oliveira TC. Necrotizing pneumonia in children submitted to thoracoscopy due to pleural empyema: incidence, treatment and clinical evolution[J]. J Bras Pneumol, 2010, 36(3): 301-305.
[8]
Westphal FL, Lima LC, Netto JC, et al. Surgical treatment of children with necrotizing pneumonia[J]. J Bras Pneumol, 2010, 36(6): 716-723.
Hsieh YC, Hsueh PR, Lu CY, et al. Clinical manifestations and molecular epidemiology of necrotizing pneumonia and empyema caused by Streptococcus pneumoniae in children in Taiwan[J]. Clin Infect Dis, 2004, 38(6): 830-835.
[13]
Lai SH, Wong KS, Liao SL. Value of lung ultrasonography in the diagnosis and outcome prediction of pediatric communityacquired pneumonia with necrotizing change[J]. PLoS One, 2015, 10(6): e0130082.