Changes in electrocardiographic parameters in children with complete left bundle branch block early after transcatheter closure of ventricular septal defect
WEI Li, LU Yong-Yi, HUA Yi-Min, ZHOU Kai-Yu, YE Qiang-Hua, WANG Chuan, WANG Xiao, YAN Song, LIU Ju-Fang
Department of Pediatrics, West China Second University Hospital/Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, Sichuan University, Chengdu 610041, China
Abstract：Objective To observe the changes in electrocardiographic parameters in children with complete left bundle branch block (CLBBB) after the transcatheter closure of simple ventricular septal defect (VSD). Methods A total of 21 children with CLBBB early after transcatheter closure of perimembranous VSD were recruited. Another 21 children without any type of arrhythmia after transcatheter closure of perimembranous VSD were enrolled as the control group. The sex, age, and the size of occluder were matched between the two groups. The changes in the following indices were compared between the two groups:left ventricular voltage, QT interval, corrected QT interval (QTc), QT dispersion (QTd), corrected QT dispersion (QTcd), JT dispersion (JTd), and corrected JT dispersion (JTcd) on the electrocardiogram before transcatheter closure and at 1, 3, 5, 30 days after transcatheter closure. Results Left ventricular voltage and JTcd changed with operation time in the CLBBB and control groups (P < 0.05). There were interaction effects between time and grouping in the changes in left ventricular voltage and QTd (P < 0.05). There was a significant difference in JTcd between the CLBBB and control groups (P < 0.05). There was also a significant difference in left ventricular voltage between the CLBBB and control groups at 3 and 5 days after the transcatheter closure (P < 0.05). Conclusions There are significant differences in electrocardiographic left ventricular voltage and JTcd between VSD children with and without CLBBB early after transcatheter closure. JTcd might be useful in predicting the development of CLBBB early after transcatheter closure of VSD.
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