Abstract:Objective To systematically review the prevalence of pediatric asthma in the rural areas of China, and to provide data for the prevention and treatment of pediatric asthma. Methods PubMed, Cochrane, China National Knowledge Infrastructure, Wanfang Database, and Embase were searched for cross-sectional studies on the prevalence of pediatric asthma in the rural areas of China published up to August 31, 2019. Two researchers independently conducted preliminary screening and data extraction. Stata 14.0 and R software were used to perform a Meta analysis of prevalence rate. Subgroup analysis was also performed. Results A total of 24 articles were reviewed, with a sample size of 212 814 children, among whom there were 3 254 children with asthma, with an overall prevalence rate of 2.02% (95%CI: 1.67%-2.36%). Boys had a significantly higher prevalence rate than girls (3.64% vs 2.03%, P Conclusions The prevalence rate of pediatric asthma is relatively low but tends to increase in the rural areas of China. Boys have a higher prevalence rate of asthma than girls, and the prevalence rate is higher in South China. Preschool children have the highest prevalence rate.
LI Li-Xiang,LIN Shu-Zhen,ZHANG Ren-Pan et al. Prevalence of pediatric asthma in the rural areas of China: a Meta analysis[J]. CJCP, 2020, 22(4): 380-386.
Papi A, Brightling C, Pedersen SE, et al. Asthma[J]. Lancet, 2018, 391(10122):783-800.
[2]
Ellwood P, Asher MI, Billo NE, et al. The Global Asthma Network rationale and methods for Phase I global surveillance:prevalence, severity, management and risk factors[J]. Eur Respir J, 2017, 49(1):pii:1601605.
Ebmeier S, Thayabaran D, Braithwaite I, et al. Trends in international asthma mortality:analysis of data from the WHO Mortality Database from 46 countries (1993-2012)[J]. Lancet, 2017, 390(10098):935-945.
[5]
Khambalia AZ, Seen LS. Trends in overweight and obese adults in Malaysia (1996-2009):a systematic review[J]. Obes Rev, 2010, 11(6):403-412.
Zhu WJ, Ma HX, Cui HY, et al. Prevalence and treatment of children's asthma in rural areas compared with urban areas in Beijing[J]. Chin Med J (Engl), 2015, 128(17):2273-2277.
[13]
Celedón JC, Palmer LJ, Xu X, et al. Sensitization to silk and childhood asthma in rural China[J]. Pediatrics, 2001, 107(5):E80.
[14]
Wang D, Xiao W, Ma D, et al. Cross-sectional epidemiological survey of asthma in Jinan, China[J]. Respirology, 2013, 18(2):313-322.
[15]
Zou Y, Jin HX, Wang RS, et al. Comparison of risk factors for recurrent respiratory infections between urban and rural preschool children in Yiwu, China[J]. World J Pediatr, 2012, 8(2):145-150.
[16]
Yang Z, Zheng W, Yung E, et al. Frequency of food group consumption and risk of allergic disease and sensitization in schoolchildren in urban and rural China[J]. Clin Exp Allergy, 2015, 45(12):1823-1832.
Valet RS, Gebretsadik T, Carroll KN, et al. High asthma prevalence and increased morbidity among rural children in a Medicaid cohort[J]. Ann Allergy Asthma Immunol, 2011, 106(6):467-473.
[32]
Parsons MA, Beach J, Senthilselvan A. Association of living in a farming environment with asthma incidence in Canadian children[J]. J Asthma, 2017, 54(3):239-249.
Guan WJ, Zheng XY, Chung KF, et al. Impact of air pollution on the burden of chronic respiratory diseases in China:time for urgent action[J]. Lancet, 2016, 388(10054):1939-1951.
[35]
Wlasiuk G1, Vercelli D. The farm effect, or:when, what and how a farming environment protects from asthma and allergic disease[J]. Curr Opin Allergy Clin Immunol, 2012, 12(5):461-466.
[36]
House JS, Wyss AB, Hoppin JA, et al. Early-life farm exposures and adult asthma and atopy in the Agricultural Lung Health Study[J]. J Allergy Clin Immunol, 2017, 140(1):249-256.e14.
Fuchs O, Bahmer T, Rabe KF, et al. Asthma transition from childhood into adulthood[J]. Lancet Respir Med, 2017, 5(3):224-234.
[39]
Song N, Shamssain M, Zhang J, et al. Prevalence, severity and risk factors of asthma, rhinitis and eczema in a large group of Chinese schoolchildren[J]. J Asthma, 2014, 51(3):232-242.
[40]
Li F, Zhou Y, Li S, et al. Prevalence and risk factors of childhood allergic diseases in eight metropolitan cities in China:a multicenter study[J]. BMC Public Health, 2011, 11:437.
Wang J, Zhao Z, Zhang Y, et al. Asthma, allergic rhinitis and eczema among parents of preschool children in relation to climate, and dampness and mold in dwellings in China[J]. Environ Int, 2019, 130:104910.