Advances in nutritional support for children undergoing hematopoietic stem cell transplantation

ZHANG Ting; JIANG Mi-Zu

doi:10.7499/j.issn.1008-8830.2310014

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Chinese Journal of Contemporary Pediatrics ›› 2024, Vol. 26 ›› Issue (3) : 308-314. DOI: 10.7499/j.issn.1008-8830.2310014

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Advances in nutritional support for children undergoing hematopoietic stem cell transplantation

ZHANG Ting, JIANG Mi-Zu

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Abstract

Hematopoietic stem cell transplantation (HSCT) is a therapeutic option for various potentially life-threatening malignant and non-malignant diseases in children, such as malignancies, immunodeficiency syndromes, severe aplastic anemia, and inherited metabolic disorders. During transplantation, many factors can affect the nutritional status of the children, including radiotherapy, chemotherapy, gastrointestinal disorders, graft-versus-host disease, and medications. Malnutrition has been associated with decreased overall survival and increased complications in children undergoing HSCT, making nutritional support a crucial component of their management. However, currently, there is a lack of guidelines or consensus on nutritional support for children undergoing HSCT in China. Therefore, this review summarizes the progress in nutritional support for children undergoing HSCT, aiming to provide clinical guidance.

Key words

Hematopoietic stem cell transplantation / Enteral nutrition / Parenteral nutrition / Child

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ZHANG Ting, JIANG Mi-Zu. Advances in nutritional support for children undergoing hematopoietic stem cell transplantation[J]. Chinese Journal of Contemporary Pediatrics. 2024, 26(3): 308-314 https://doi.org/10.7499/j.issn.1008-8830.2310014

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