辅助生殖技术对双胎出生体重不一致的影响

doi:10.7499/j.issn.1008-8830.2307034

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Abstract Objective To explore the association between assisted reproductive technology (ART) and birth weight discordance in twins (BWDT). Methods A retrospective analysis was conducted on twin infants born between January 2011 and December 2020 at the Third Affiliated Hospital of Guangzhou Medical University, with complete basic birth data. The impact of ART on the occurrence of BWDT was identified by the multivariate logistic regression analysis. Results A total of 3 974 pairs of twins were included, with 1 431 conceived naturally and 2 543 through ART. Neonates in the ART group had higher birth weights than those in the naturally conceived group (P<0.001). The incidence of BWDT was lower in the ART group compared to the naturally conceived group (16.17% vs 21.09%, P<0.001). The multivariate logistic regression analysis, adjusting for confounding factors such as maternal age, parity, pre-pregnancy body mass index, gestational diabetes, hypothyroidism, gestational age, and chorionic properties, showed no significant difference in the risk of BWDT between the ART and naturally conceived groups (P>0.05). Conclusions ART is not associated with the risk of BWDT.

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	Articles by authors
	LI Qiu-Ying
	ZHANG Hui
	CHEN Qian
	SHI Bi-Jun
	TAN Xiao-Hua
	CUI Qi-Liang

Key words： Birth weight discordance Assisted reproductive technology Twins Neonate

Received: 12 July 2023

Cite this article:

LI Qiu-Ying,ZHANG Hui,CHEN Qian et al. Impact of assisted reproductive technology on birth weight discordance in twins[J]. CJCP, 2023, 25(12): 1239-1245.

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http://www.zgddek.com/EN/10.7499/j.issn.1008-8830.2307034 OR http://www.zgddek.com/EN/Y2023/V25/I12/1239

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