Churg-Strauss syndrome in children: a case evolving in endomyocardiopathy
LU Shan, ZHOU Wen-Yan, ZHOU Wei, LI Zhao-Ping, CHANG Yan-Mei, WEI Ling, TONG Xiao-Mei
Department of Pediatrics, Peking University Third Hospital, Beijing 100083, China
Abstract A 13-year-old girl presented with a 1-month history of progressive exertional dyspnea (NYHA class Ⅳ) and exophthalmos for 6 months. She had a history of long-standing asthma and the presence of allergy. Hypereosinophilia and increased serum IgE levels (2 472 IU/mL) were observed. Chest radiography and a high resolution CT scan documented a massive interstitial pulmonary infiltration. Echocardiography confirmed mild tricuspid regurgitation, apical obliteration of the right ventricle by fibrocalcific thickening of the endocardium and echogenic material suggestive of thrombosis. Churg-Strauss syndrome with cardiac involvement (endomyocardiopathy) was diagnosed. The patient received anticoagulation and corticosteroid therapy. In view of rapidly progressive severe endomyocardiopathy and stable hematology, the patient was referred for cardiac surgery. Histopathological examination of resected specimens confirmed laminated thrombus but without any trace of eosinophils embedded.
Key words ：
Angitis
Endomyocardiopathy
Child
Cite this article:
LU Shan,ZHOU Wen-Yan,ZHOU Wei et al. Churg-Strauss syndrome in children: a case evolving in endomyocardiopathy[J]. 中国当代儿科杂志, 2008, 10(5): 625-628.
LU Shan,ZHOU Wen-Yan,ZHOU Wei et al. Churg-Strauss syndrome in children: a case evolving in endomyocardiopathy[J]. CJCP, 2008, 10(5): 625-628.
URL:
http://www.zgddek.com/EN/ OR http://www.zgddek.com/EN/Y2008/V10/I5/625
[1]
WANG Jun, LANG Yong-Bin, DU Jiang-Hua, CHEN Zhen, ZHU Deng-Na, ZHANG Yong, LI Meng-Yue, TONG Pei. Effect of suspension exercise training on motor and balance functions in children with spastic cerebral palsy
[2]
DUAN Lian, HU Guo-Huang, JIANG Meng, ZHANG Cheng-Liang, DUAN Yan-Ying. Association of hypoalbuminemia with acute kidney injury in children after cardiac surgery
[3]
CHEN Zai-Sheng, ZHENG Yong-Zhi, CHEN Yi-Qiao, GAO Qin-Li, LI Jian, SHEN Jian-Zhen. Clinical features and prognosis of children with mature B-cell non-Hodgkin's lymphoma: an analysis of 28 cases
[4]
ZHAO Min. Clinical phenotypes and a genetic analysis of patients with Sotos syndrome
[5]
PENG Jia-Yu, HUANG Ying, OU Jiang-Yan, YANG Yang. Association of blood lipids with childhood asthma
[6]
XIU Xiao-Ying, CUI Yu-Xia, HUANG Yu-Ying, FAN Li, YUAN Jun, TIAN Zhu-Li. Association of vitamin D level with asthma control and pulmonary function in asthmatic children aged 4-12 years
[7]
FAN Mei-Rong, WANG Gui-Jie, YU Xin-You. Clinical and genetic features of ring chromosome 13 syndrome: an analysis of one case
[8]
YOU Jie-Yu. Features and management of very early onset inflammatory bowel disease
[9]
ZHAO Yun-Jing, MA Hong-Wei. NIPBL gene mutations in two children with Cornelia de Lange syndrome
[10]
LUO Ye, ZHAO Hua, LIU Rui-Fang, SHI Hong-Juan. Current status of exclusive breastfeeding for the second child and factors influencing exclusive breastfeeding in the context of the universal two-child policy
[11]
ZHANG Yi-Bin, WANG Yan-Peng, LIU Jing. Research advances in the role of aptamers in the diagnosis and targeted therapy of pediatric cancer
[12]
WU Yuan-Yuan, CAI Sheng-Yang, HUANG Wei, LI Si-Si, LI Wei, DONG Ao. Clinical and laboratory characteristics of juvenile myelomonocytic leukemia
[13]
QIU Ting, GUO Bing-Bing, WANG Li-Zhen, ZHANG Heng, XU Yin, JIANG Xin-Ye. Association between overweight/obesity in parents and autism spectrum disorders in offspring
[14]
ZHU Ying, DONG Yang, XU Da-Liang, JIANG Jia-Yun, WU Lin, KE Rui-Juan, FANG Shao-Han, PENG Yin. Clinical effect and mechanism of hemoperfusion in treatment of children with severe abdominal Henoch-Schönlein purpura
[15]
CHENG Yan-Qin, ZHAI Xiao-Wen. Clinical application of minimal residual disease detection in childhood acute leukemia
