Therapeutic Effect of L-thyroxine on Childhood Hypothyroidism
SHI Lin, RUAN Guo-Tao, HU Hong-Bing
Department of Pediatrics, Maternal and Child Health Hospital, Haikou 570102, China
Abstract Objective To explore the therapeutic effect, safety and appropriate dosage of Lthyroxine on child hypothyroidism. Methods In the treatment group (L Group) Lthyroxine was used (n =40), while in the control group (T Group) dry thyroxine was used (n=35). The cl inical behavior, TSH, T4, T3 and bone ages were observed. Results Significant difference in remission in the 4th week of therapy was found between the 2 groups.The L Group was significantly higher than the T Group (χ 2=13.78, P<0.01). There was a significant difference in the 4th we ek in the convalescence of TSH and T4. The L Group was higher than the T Group (χ2=24.75，P<0.05). No hyperthyroidism was found in the L Group. Conclusions Lthyroxine therapy for child hypothyroidism resu lts in significant improvement in brain development and milder side effects than tranditional treatment. Lthyroxine may be considered for clinical use.
Key words ：
L-Thyroxine
Hypothyroidism
Child
Cite this article:
SHI Lin,RUAN Guo-Tao,HU Hong-Bing. Therapeutic Effect of L-thyroxine on Childhood Hypothyroidism[J]. 中国当代儿科杂志, 2000, 2(5): 323-325.
SHI Lin,RUAN Guo-Tao,HU Hong-Bing. Therapeutic Effect of L-thyroxine on Childhood Hypothyroidism[J]. CJCP, 2000, 2(5): 323-325.
URL:
http://www.zgddek.com/EN/ OR http://www.zgddek.com/EN/Y2000/V2/I5/323
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