Effect of Pulmicort Aerosol on Childhood Asthma
CHEN Qiang, ZHU Lu-Qi, LIU Jian-Mei, GUO De-Hua, YU Ding-Ying, HUANG Wei, CHEN Ren-Jun
Department of Pediatrics, Jiangxi Children's Hospital, Nanchang 330006
Abstract Objective To observe the differences of peak expiratory flow (PEF), and serum eosinophil cationic protein (ECP) before and after Pulmicort aerosol inhalation for childhood asthma. Methods 113 asthmatic children treated with Pulmicort aerosol [(200～800) μg/d] for (3～12) months were studied. PEF was monitored with a peak flowmeter, and ECP was measured using fluoroimmunoassay (Pharmacia CAP system) before and after the treatment. Results PEF remarkably increased after inhalation therapy. Its percentage accounting for anticipant value after 3 m, 6 m, and 1 year ( 93.6 ± 5.4 , 93.0 ± 4.2 , 94.5 ± 4.5 ) had statistical significance compared with the percentage before inhalation therapy ( 70.4 ± 19.1 ) (P< 0.01 ). Serum ECP after the treatment [( 7.5 ± 2.7 ) μg/L] was significantly lower compared with ECP prior to inhalation [( 24.0 ± 17.1 ) μg/L] (P< 0.01 ). Conclusions Pulmicort aerosol appears to be an effective middle- and long-term therapy to treat and prevent childhood asthma because of its low incidence of side effects, its safety, and simplicity of use.
Key words ：
Childhood asthma
Pulmicort
Peak expiratory flow
Eosinophil cationic protein
Cite this article:
CHEN Qiang,ZHU Lu-Qi,LIU Jian-Mei et al. Effect of Pulmicort Aerosol on Childhood Asthma[J]. 中国当代儿科杂志, 2000, 2(3): 152-154.
CHEN Qiang,ZHU Lu-Qi,LIU Jian-Mei et al. Effect of Pulmicort Aerosol on Childhood Asthma[J]. CJCP, 2000, 2(3): 152-154.
URL:
http://www.zgddek.com/EN/ OR http://www.zgddek.com/EN/Y2000/V2/I3/152
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