Abstract OBJECTIVE: This study examined the levels of exhaled nitric oxide (eNO) and peripheral blood eosinophils (EOS) as well as the correlation between the two markers in children with bronchial asthma (AS)，AS complicated by allergic rhinitis (AS/AR) and chronic cough variant asthma (CVA), in order to explore the value of eNOS detection in children with AS. METHODS: The eNO level was measured using light-emitting electrochemical photometry in 12 children with AS, 29 children with AS/AR and 10 children with CVA. Peripheral blood EOS was counted by blood cell counter (Coulter JT). Forced expiratory volume in one second (FEV1) was assessed by lung function measurement. Thirty children without atopic disease and acute respiratory infection as well as without a family history of atopic diseasea served as the control group. RESULTS: The levels of eNO and blood EOS in the AS, the AS/AR and the CVA groups were significantly higher than those in the control group (P0.05) in the AS group. CONCLUSIONS: NO is highly expressed in children with symptoms of atopy and can reflect the levels of eosinophilic airway inflammation in children with AS.［Chin J Contemp Pediatr, 2009, 11 (12):986-988］
GE Chun-Long,HAO Chuang-Li,TANG Ning-Bo et al. Changes of exhaled nitric oxide and peripheral blood eosinophils in children with asthma[J]. 中国当代儿科杂志, 2009, 11(12): 986-988.
GE Chun-Long,HAO Chuang-Li,TANG Ning-Bo et al. Changes of exhaled nitric oxide and peripheral blood eosinophils in children with asthma[J]. CJCP, 2009, 11(12): 986-988.
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